Cefotaxime for cats instructions for use: can lidocaine be injected into cats?

In veterinary practice, the human drug “Cefotaxime” for cats is used as an antibacterial agent when other medications are powerless and antibiotic therapy cannot be avoided. The instructions for use describe in detail all the features of using the medicine. But before you give your kitten Cefotaxime, you need to consult with a veterinarian who, based on a diagnostic examination, will establish effective, but at the same time safe, dosages for the animal. Experienced veterinarians strongly do not recommend treating your pet with this medication yourself.

Composition and properties

The pharmaceutical drug Cefotaxime is sold in the form of a solution for parenteral administration containing the active ingredient cefotaxime anhydrous. This substance has a pronounced antibacterial effect, which consists in disrupting the synthesis of the cell walls of the pathogenic microorganism, after which they lose the ability to reproduce and die. "Cefotaxime" is active against gram+ and gram-bacteria, strains of Pseudomonas aeruginosa, acenitobacter, and Helicobacter pylori.

Release form and composition of the medicinal product

Cefotaxime is available in powder form in glass bottles with a sealed cap. The color of the contents of the bottles is white. In some cases, the powder has a yellow tint, but this does not mean that it is unsuitable. The medicine goes on sale in three dosages - 1000, 500 and 250 milligrams. The packaging of the medicine consists of 1 or 5 bottles of the drug and instructions. The antibiotic is not available in tablet or suspension form.

The drug contains no additional substances. The only active component is cefotaxime sodium, which belongs to the third generation semisynthetic cephalosparins. The drug is administered intramuscularly or intravenously.

Reviews from veterinarians

Vladimir, veterinarian with 8 years of experience:

“I consider Ceftriaxone one of the best antibiotics. It always does a great job of killing bacteria. But I want to warn pet owners that the drug is strong and should not be used on their own. The main advantages are efficiency, availability and low price.”

Valentina, veterinarian with 5 years of experience:

“It’s difficult to express an opinion about this antibiotic in a nutshell. On the one hand, it is effective and can become a lifesaver for severe pathologies, but on the other hand, it is a rather dangerous drug. If used incorrectly, it can cause serious side effects. I usually prefer weaker antibacterial agents, and only use Ceftriaxone in emergency cases.”

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Ceftriaxone is a third-generation antibiotic that fights against many pathogens.

It is considered an antibacterial agent, which is prescribed for both people and pets (including the antibiotic Ceftriaxone prescribed for cats).

Indications for use: Ceftriaxone is considered a powerful antibiotic and can only be prescribed by a doctor.

Last help

Lidocaine is most often used to euthanize hopelessly ill cats. But for such a death to be truly easy, an ampoule with the drug is not enough. Lidocaine blocks the passage of cardiac signals and causes vascular collapse. To euthanize a cat, it must be injected into a vein, not into a lung - this will be a painful death from respiratory paralysis.

Humane euthanasia is a complex process. So you can euthanize a cat with Lidocaine at home and without suffering, but to do this you will still have to contact a veterinarian. Doing it yourself will be cruelty to the animal.

There are several rules for euthanizing cats with Lidocaine.

Before deciding to euthanize, you should consult with several veterinarians to ensure that the disease is incurable. The sick appearance of an animal does not mean much - perhaps simple treatment will help him.
Before administering Lidocaine, general anesthesia must be used.
The dose of the drug is determined by the veterinarian - it depends on the age, weight, and condition of the animal.
You should only seek such a service from a trusted doctor, known for his humane treatment of tailed patients.

However, a true cat lover, attached to his purr, will fulfill all these requirements without any reminders. After all, he will think not about saving money, but about the interests of the animal.

There are cat lovers who oppose the euthanasia of even terminally ill older animals. But their point of view is objectionable, since in this case the last days of their pet will be filled with dubious “pleasures”. Properly carried out euthanasia under general anesthesia (for example, Lidocaine) in a hopeless situation is the only correct decision in case of an incurable disease.

Trying to treat animals on your own is just as bad as trying to treat people. For its affection and goodwill, the cat deserves human treatment. And Lidocaine is a drug that can bring him more than just benefits.

Instructions for use

For kittens, the drug is diluted with Novocaine.
Your pet should be treated with antibiotics strictly as prescribed by your veterinarian. For kittens, Cefotaxime is injected in a dosage corresponding to the body weight of the animal. Before the injection, dilution of the powder is required and usually Novocain and injection water are used for this purpose. Lidocaine is strictly contraindicated for kittens as an anesthetic. To prepare the solution you will need 1 g of Cefotaxime and 2 ml of Novocaine and sterile water. Drug doses are calculated based on the weight of the animal. So, for small individuals weighing less than 2 kg, 0.5 ml of antibacterial solution is prescribed, and heavier cats are allowed 1 ml. Injections are given to the cat once a day, but usually experienced veterinarians recommend dividing the daily dose into several injections. The duration of the treatment course is 7-10 days.

Veterinarians insist that you should not stop treatment, even if the accompanying symptoms have passed and the purr feels great, it is extremely important to complete the therapeutic course.

Overdose

If the dose of the drug is exceeded, the pet may suffer from shortness of breath. Owners, exceeding the doses recommended by a veterinarian, expose the cat’s body to poisoning with antibiotic medicinal substances. Cefotaxime intoxication manifests itself in the form of fever, shortness of breath, temporary hearing loss, and the development of problems in the dermis and gastrointestinal tract. Since there is no specific antidote, the cat undergoes hemodialysis and, if necessary, symptomatic therapy.

Application procedure

Cefotaxime is given to cats by injection. If you take it orally, it is not absorbed. The release form of the drug is powder. Before use, it should be diluted - prepare a solution for injection. Dilution is carried out with Novocaine.

Lidocaine cannot be used as an anesthetic for cats.

When preparing the solution take:

"Cefotaxime" - 1 gr.
"Novocaine" - 2 ml.
Water for injections – 2 ml.

You can give a Cefotaxime injection to a cat by intramuscular injection or inject it intravenously using a catheter. Only a doctor should give an intravenous injection.

The dosage of Cefotaxime for a cat is calculated taking into account the pet’s body weight:

if the cat weighs less than 2 kg - 0.5 ml of antibiotic solution;
cats weighing more than 2 kg - 1 ml of Cefotaxime solution.

A cat should be injected with Cefotaxime once a day, but often the doctor advises dividing the required volume into several doses. Treatment lasts from 7 to 10 days, it all depends on the clinical picture of the disease. Even if the signs of the disease have gone away and the pet’s health has improved, the injections must continue to be given in the same dose. The entire course prescribed by the doctor must be completed in full.

When treating a cat with Cefotaxime, strictly follow the dosage prescribed by your doctor.

What is treated with Cefotaxime?

Cats, like any pet, sometimes get sick. This happens more often with animals that are outdoors. They have diseases that people also get, but there are exclusively cat diseases. In most cases of infection in a pet, doctors prescribe Cefotaxime. Instructions for use

"Cefotaxime" for cats describes the use of the drug for infectious diseases:

respiratory organs; organs of the excretory system; organs of hearing and smell; brain; bone and muscle tissue; organs of the digestive system; organs of the reproductive system; wounds and burns.

Important! Treatment with Cefotaxime should only be carried out strictly as prescribed by a veterinarian.

Action of Lidocaine

Lidocaine is available in the form of ampoules. They contain a clear solution that has no characteristic odor. The volume of one ampoule is 2 ml. The package contains 5 ampoules. Instructions for use are included with each package.

The active ingredient of the drug is lidocaine monohydrate. Its effect is complemented by caustic soda and sodium chloride. The excipient is water.

The medication can be administered either intramuscularly or via a dropper. The latter option allows you to quickly get the effect of the active substance (in 20 minutes).

Due to the fact that the neuron membrane is restored, a local anesthetic effect is manifested. In this case, the process of excitation occurrence slows down, because the ability of the membrane to release sodium ions, which compete with calcium ions, decreases.

Lidocaine promotes vasodilation and also eliminates pain. This drug is best absorbed when administered intramuscularly. The active substance accumulates in liver cells and is excreted from the body after 10 hours.

Possible limitations and negative phenomena

The strong antibacterial drug Cefotaxime should be used for cats only after tests and a diagnostic examination. Incorrect dosages are dangerous due to the development of side symptoms and can even lead to the death of the animal. And also the risk of negative effects when using Cefotaxime increases if you inject a cat with it, neglecting contraindications. So, the antibiotic is not suitable for purrs that have the following pathological conditions:

liver pathologies;
disorders of the kidneys;
ulcerative lesions of the gastrointestinal tract;
individual intolerance to the components of the drug.

The drug is toxic to lactating females and can cause disorders of various body systems in animals. "Cefotaxime" will be dangerous for a small kitten and a pregnant or lactating cat. A broad-spectrum antibiotic can cause the following negative effects:

urge to vomit, constipation, flatulence;
allergic reactions;
breathing problems;
changes in blood fluid characteristics;
failure of the kidneys and liver;
difficulty urinating;
painful sensations in the head, vertigo;
signs of fungal infection.

There may be irritation at the injection site and an increase in body temperature. To minimize the likelihood of negative effects, you need to use the antibiotic correctly, strictly following all the veterinarian's instructions. If even the slightest undesirable symptoms appear from Cefotaxime injections, you need to stop therapy and urgently take your pet to a veterinary clinic.

Side effects

The drug "Cefotaxime", like "Ceftriaxone", is often prescribed to cats and dogs in veterinary practice. But it is not suitable for all animals. It is not uncommon for cats to experience problems with the functioning of individual organs or even systems when using it. Side effects after taking the medicine may occur :

malfunction of the digestive system (vomiting, flatulence, constipation); signs of allergies (urticaria); breathing problems; malfunctions of the liver and kidneys; changes in blood composition; difficulty urinating; manifestations of signs of fungal infection; dizziness, headache.

Irritation may occur at the injection site. There is an increase in body temperature.

To avoid any unforeseen situations when treating a cat, you must completely follow the doctor’s instructions. And if even minor symptoms of side effects appear, stop taking the drug and immediately contact your veterinarian.

Contraindications

Cefotaxime is a fairly strong antibiotic. Therefore, it is prescribed only after tests have been carried out and the animal has been examined. After all, erroneous use can cause side effects or even the death of your pet. Like any drug, it has a certain list of contraindications for which the use of Cefotaxime is strictly prohibited :

with kidney failure;
for liver diseases;
during pregnancy and lactation;
kittens;
with peptic ulcer of the stomach or intestines;
with intolerance to antibiotics, penicillin.

Contraindications to the use of the drug

1. Treatment of various infectious diseases:

Gastrointestinal tract;
Respiratory system;
Biliary tract;
Kidney and urinary tract;
Osteomyelitis (bone infection);
Meningitis (bacterial infection of the membranes of nerve tissue).

2. Prevention of postoperative complications.

3. Prevention of infection of abrasions and bites from other animals, along with anti-rabies serum.

Ceftriaxone is partially excreted in the urine, so it is very important to consider the condition of the animal's kidneys before administration. For a cat with a history of liver, kidney and gall bladder diseases, the drug is either contraindicated, or the dosage of administration is adjusted.

The medicine is prohibited for the treatment of kittens, since the toxic effect of the medicine on the delicate body of the animal outweighs the benefits. Ceftriaxone should not be given to pregnant or lactating cats. Pregnant cats may have a miscarriage after administration of the drug or subsequently give birth to sick offspring. In nursing cats, the medicine passes into the milk and has a toxic effect on kittens.

It is very often used for the following pathologies of the respiratory system:

pneumonia;
pleurisy;
abscesses;
bronchitis.

Also, the remedy in question is effective for:

bacterial meningitis;
endocarditis;
postoperative complications;
septicemia;
infections of soft tissues and bones;
Lyme disease;
diseases of the urinary tract, throat, ear, nose, kidneys;
infections of joints and bones;
abdominal infections;
infections that occur against the background of immunodeficiency.

It should also be noted that Cefotaxime injections are often prescribed to prevent infections that develop after surgical interventions (including urological, obstetric-gynecological, gastrointestinal, etc.).

We will tell you how to dilute the Cefotaxime injection below. It should be noted that this product does not have a very long list of contraindications. According to the instructions, this medication is not prescribed for:

bleeding;
pregnancy;
individual hypersensitivity to the active ingredient;
enterocolitis (including history).

Is it possible to administer Cefotaxime solution to a child? Injections for children (reviews of the effectiveness of the mentioned medicine will be presented at the end of the article) are allowed only when the patient reaches the age of 2.5 years (for intramuscular administration).

With extreme caution, the medication is prescribed to newborn babies, during breastfeeding (since the drug is excreted in small quantities in breast milk), as well as in the presence of chronic renal failure and UC (including a history).

In case of pathology of the renal and hepatic systems, the patient is required to undergo additional medical examination in order to obtain a conclusion about the absence of contraindications to antibiotic therapy.

How to store?

According to the instructions, the antibacterial drug requires special storage conditions. Cefotaxime powder should be placed in a dry place, protected from light, where the air temperature does not rise above 25 degrees Celsius. The shelf life of a closed ampoule is 2 years. After diluting the powder with injection water, the prepared solution should be stored for no longer than 24 hours. An expired antibiotic must be disposed of; injecting it into a cat is strictly contraindicated. Small children and animals should not have access to the Cefotaxime package.

Price

Vials of Cetofaxin are packaged in cardboard boxes of 5-10 pcs. But in many pharmacies they are sold individually. The cost of one bottle is on average 31 rubles. Pack of 5 bottles 100-160 rub. The shelf life of a closed bottle is 3 years. Use the prepared solution immediately and cannot be stored. The main danger of a purulent focus is the risk of developing sepsis. Pyogenic microflora can enter the bloodstream and quickly spread throughout the body. Treatment is prescribed in a course and must be followed. Repeated treatment with the same antibiotic may be completely useless. The drug has high therapeutic activity and minimal toxic effects on the animal body. Cetofaxine treats such common diseases as cystitis, pneumonia, chlamydia, purulent otitis, abscess, burns, gastrointestinal infections, etc. An important advantage is the price of the medicine, which is significantly lower than imported analogues. Rehabilitation therapy after treatment is of particular importance. Since this drug has a strong effect on the body, manifestations of dysbacteriosis, impaired vitamin metabolism, and decreased immunity are common. First of all, the pet should adjust its diet by including mainly easily digestible foods and special prebiotics in the diet.

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Side effects

These antibiotics have side effects. When using Cefotaxime, the following unpleasant symptoms are possible:

Allergies accompanied by hives and fever.
Oliguria.
Dizziness and headaches.

As a result of using the drug, disorders of the digestive system - diarrhea, nausea - may occur. Another side effect is nosebleeds.

Side effects also occur when using Lidocaine. As a result of its use, the following manifestations are possible:

feeling of dry mouth;
chronic fatigue;
dyspnea;
decreased metabolism.

The listed adverse reactions are often accompanied by a feeling of heaviness in the stomach and nausea. Anaphylactic shock may occur.

Olga, 27 years old, Moscow: “To treat a sore throat, the doctor prescribed Cefotaxime and Lidocaine. I began to feel better already on the third day after using them.”

Natasha, 30 years old, Astrakhan: “When my husband had sinusitis, the doctor recommended injections of Lidocaine and Cefotaxime. These medications give a quick effect if you take into account the doctor’s recommendations.”

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Ekaterina, 22 years old, Nizhny Novgorod: “The combination of Cefotaxime and Lidocaine is effective in the treatment of tonsillitis. I felt better on the second day, but the course was completed completely.”

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Price and analogues of antibiotics

Now you know how to dilute Cefotaxime injections. But what is their dosage? It depends on the indications and severity of the disease.

For urinary tract infections, as well as for uncomplicated infections, the drug is administered intravenously or intramuscularly, 1 g every 9-12 hours.

For moderate infections - 1-2 g every 12 hours.

For uncomplicated acute gonorrhea, the medication is prescribed intramuscularly in a dosage of 1 g (single dose).

For severe infection (for example, meningitis), the drug is used intravenously, 2 g every 6-9 hours. The maximum dose per day is 12 g. The duration of therapy is determined individually.

To prevent the development of infectious diseases, before surgery, the patient is given a single dose of 1 g of Cefotaxime during induction of anesthesia. If required, the injection is repeated after 6-12 hours.

During a caesarean section, during the process of applying clamps to the umbilical vein, the drug is administered intravenously in an amount of 1 g. Then, after 6-12 hours, an additional injection is given in the same dose.

The cost of the drug in question depends on the network’s markup and sales region. On average, ampoules-bottles (5 pieces of 1 g each) can be bought for 160-170 rubles.

If necessary, this medication can be replaced with similar drugs such as Klaforan, Cephabol and Cefosin.

However, it should immediately be noted that these medications can only be used after consulting a doctor.

In pediatric practice, this medication is often prescribed as an antimicrobial agent. As a rule, this is done in cases where other antibiotics do not provide a positive therapeutic effect.

Consumer reviews of Cefotaxime injections are more positive. Patient reports confirm its high antimicrobial effectiveness. However, you can also find responses that directly indicate the presence of a large number of negative reactions observed after treatment (bloating, dysbacteriosis, colic, etc.).

Ceftriaxone is an effective and powerful antibiotic that is used not only for cats, but also for people. Its unique feature is its wide spectrum of action, but if used incorrectly or in the wrong dosage, it can cause serious adverse reactions, even death, so it is strictly forbidden to use it without a doctor’s prescription.

general description

Ceftriaxone is available in the form of a white or yellowish powder. For its packaging, glass bottles are used, which are sealed with rubber stoppers and closed with aluminum caps.

They allow you to maintain the tightness of the drug. Since the drug is used in the form of injections, the powder is diluted with water for injection or novocaine before use.

0.25, 0.5, 1 or 2 g of ceftriaxone sodium salt is placed in the vials.

Important! The antibiotic should not be used after the expiration date, so always pay attention to the date on the package.

How it works and when to use it

Ceftriaxone is a third-generation antibiotic from the cephalosporin series. The principle of its action is that it prevents the synthesis of cell membranes in pathogenic microorganisms.

As a result of this action, the microbes die. The antibiotic begins to act 2-3 hours after introduction into the body.

The drug is effective against various bacterial infections:

staphylococcus;
streptococci;
coli;
proteas;
enterococcus;
salmonella, etc.

Treatment of cats with Ceftriaxone is recommended in the following cases:

with otitis;
for sepsis;
for bronchitis, pneumonia and other infectious diseases of the respiratory tract;
for cystitis and other bacterial inflammations of the genitourinary system;
when affected by infection of the liver and biliary tract;
with chladimiosis;
with meningitis;
for osteomyelitis and other bone pathologies of bacterial origin;
for infectious inflammation of soft tissues;
for gastrointestinal infections;
for other pathologies caused by antibiotic-sensitive microorganisms.

The medicine is also prescribed in the postoperative period to prevent complications in the form of bacterial infections.

Directions for use and dosage

Medicinal powder is used to prepare a solution. It is usually administered intramuscularly. Typically, injections are given in the back thigh, where a large number of muscles are located. It is allowed to administer the medicine to animals intravenously, but this is difficult to do at home. The procedure can only be performed by a qualified doctor.

Note! Injecting Ceftriaxone subcutaneously into cats is strictly prohibited.

The powder can be diluted with water for injection or 1% novocaine. The second option is more preferable if the animal is not allergic to the anesthetic, since antibiotic injections are very painful.

But lidocaine should not be used to dilute antibacterial powder, since it often causes serious allergic reactions in cats, including anaphylactic shock.

In addition, lidocaine can greatly reduce blood pressure, so it is deadly for animals with cardiovascular diseases.

For cats, it is advisable to buy bottles of 0.25 g. If you add 3.5 ml of novocaine or water for injection to such a bottle, then for animals up to 2 kg you will need 0.5 ml, and for larger pets - 1 ml.

If 3.5 ml of dilution liquid is added to a bottle with 0.5 g of medicinal powder, then 0.14-0.16 ml of solution is needed per 1 kg of weight.

Injections are given once a day. When first used, it is important to monitor the animal’s condition or conduct an allergy test before starting treatment. The course usually lasts 5-10 days, but is determined solely by the veterinarian depending on the condition of the animal and the existing symptoms. If your pet's condition does not improve within 2-3 days, you should choose another antibiotic.

How to give injections?

To prepare the solution, you need to do the following:

Remove the aluminum disk in the center of the cap.
Fill the syringe with novocaine or water.
Puncture the rubber stopper and release the contents of the syringe into the vial.
Shake the bottle well until the powder is completely dissolved.
Draw the prepared solution into a syringe.
Before injecting your animal, change the needle to a new one.

It is advisable to use insulin syringes to administer Ceftriaxone. Thanks to the thin needle, the injections are less painful. I do them like this:

The cat or cat needs to be secured. It is desirable that the muscles are as relaxed as possible. There is no need to treat the injection site, just massage it lightly.
Quickly insert the needle at a 45˚ angle about 1 cm into the muscle tissue.
Slowly inject the solution.
Gently remove the needle and lightly massage the injection site, but do not apply pressure as it may hurt.

Note! Since the antibacterial agent is painful, it is recommended to alternately inject the right and left hind paws.

Advantages and disadvantages

The main advantages of using Ceftriaxone for cats include the following:

Wide spectrum of action. Acts against gram-positive and gram-negative bacteria of various types.
High efficiency. The drug belongs to the third generation antibiotics and begins to act quickly.
Availability. You can buy the medicine at any nearest pharmacy. It is not at all necessary to look for a veterinary pharmacy.
Low cost. The price of one bottle of Ceftriaxone is 20-30 rubles; no more than 10 bottles are required per course.

The drug also has significant disadvantages:

painful injections;
side effects;
risk of deterioration in health and even death in case of overdose or misuse;
the complexity of preparing the solution;
a number of contraindications.

Owner reviews

“I picked up our beauty on the street. The state of health left much to be desired. During the examination, they discovered sinusitis (mucus with pus and blood flowed from the nose). The doctor prescribed Ceftriaxone. The injections are very painful, but after the second injection the cat felt much better, and after a 7-day course she completely recovered.”

“This antibiotic almost killed my cat. Now we have serious problems with our kidneys and it is unknown whether we will be able to pull through. We were prescribed Ceftriaxone to treat pancreatitis. Later we learned that the dose was almost doubled (we did everything according to the doctor’s recommendations). I think it’s better to choose a safer drug, even if the treatment is longer.”

Reviews from veterinarians

“Ceftriaxone is a good antibiotic. In many cases there is hope for a complete recovery, but it must be used carefully. Only a doctor should calculate the dose. In my practice, there was a case when we tried to save a cat from an overdose, but, alas, our efforts were in vain. This drug is definitely not suitable for self-medication.”

“Ceftriaxone is an inexpensive but effective antibacterial agent. Quite often it is prescribed to both cats and dogs. Owners are advised to dilute the powder with novocaine. Like most antibiotics, it can cause side effects (there have even been cases of death of pets), but I believe that the drug still has more benefits.”

A pharmacological drug called Cefotaxime belongs to the list of effective new generation antibiotics. It has become widespread due to the fact that it has a wide range of effects on various types of pathogenic microorganisms and bacteria.

This makes it possible to use the drug to treat various types of diseases associated with the penetration of bacteria and viruses into the body. One more advantage of the drug Cefotaxime should be noted, which is due to the safety of its effects on the body.

It is known that antibiotics, together with treatment, have a negative effect on the human body, destroying not only pathogenic bacteria, but also beneficial microorganisms. In Cefotaxime, such negative effects are minimized.

To fully emphasize the safety of the drug, it should be noted that it can be used even for babies from 1 week of life. Let's take a closer look at what Cefotaxime is.

In what cases is an antibiotic indicated?

Instructions for using the drug Cefotaxime in the form of injections state that the antibiotic is indicated for the following diseases and pathologies:

genitourinary infections;
skin infections;
infectious diseases of the respiratory organs;
salmonellosis;
infectious wounds and burns;
diseases of the musculoskeletal system that are infectious in nature;
diseases of the ENT organs: sinusitis and tonsillitis;
abdominal infections.

These are the main diseases for which antibiotic use is indicated. The drug is also indicated for use in peritonitis, sepsis and endocarditis. This remedy is used to combat Lyme disease.

It is also prescribed for preventive purposes after surgical interventions. Doctors may prescribe the drug for developing infections against the background of immunodeficiency.

Such widespread use of Cefotaxime in the form of injections is due to its effectiveness and wide range of influence.

Release forms

Cefotaxime is available in the form of a dry powder mixture that is white in color. This antibiotic is not available in tablet form.

This form is designed for intravenous and intramuscular use. Cefotaxime is dispensed mainly in transparent glass bottles of 500 mg and 1 g.

If the animal gets worse

We cannot rule out the possibility that after an injection with Ceftriaxone, the dog will become worse - a rash, redness and soreness with lumps will appear at the injection site. This is how an allergy to the drug manifests itself; it can develop rapidly and go into anaphylactic shock.

Skin allergies similar to urticaria in a dog

Deterioration of the dog’s condition is a reason to immediately seek qualified veterinary help.

Adverse symptoms

Adverse reactions can occur if the medication is used incorrectly, with an overdose, or if Cefotaxime is administered if the patient is allergic. The main types of adverse reactions that can be caused by Cefotaxime are:

The development of allergic reactions cannot be ruled out, which can cause symptoms such as itching, bronchospasms and skin rashes in the form of urticaria. After administration of the medication, anaphylactic shock and angioedema may occur. Doctors also note that after the injection, pain may develop at the injection site. After the injections, changes in laboratory blood parameters are also observed.

In case of overdose, the following side symptoms are observed:

Tremor.
Cramping sensations.
Fever.
Hearing loss.
Loss of coordination.

Feedback from cat owners about ceftriaxone

Elena, Novorossiysk. Despite the abundance of conflicting information about the reaction of cats to ceftriaxone, my personal experience has confirmed its effectiveness.

Owners note that Ceftriaxone is effective against many infections.

I treated an 8-year-old cat with urolithiasis. The veterinarian prescribed ceftriaxone based on the results of a urine test, bacterial culture and sensitivity to antibiotics. They injected for a week, everything was fine, no side effects. I believe that such prescriptions should be made only on the basis of tests; this is an indicator of the doctor’s competence. And if such strong antibiotics are used as self-medication, then there is no point in blaming the medicine.

Ksenia, Khabarovsk. We were given ceftriaxone after sterilization surgery. Two cats were neutered at the same time. This makes it more convenient to care for them during the recovery period after castration. In the first days, they were given antibiotic drips through a catheter on their paws, which was tolerated perfectly. At home they have already switched to injections. This, of course, is still the same story! But I got used to doing them even without helpers. I put the cat on my lap, clasp all its paws in my left palm, and quickly stab it with my right hand. Everyone is alive and well.

Pharmacological properties

Ceftriaxone is effective against many harmful bacteria, including those microorganisms that are resistant to other antibacterial agents. The drug destroys the following types of pathogens:

staphylococci;
E. coli;
streptococci;
salmonella;
clostridia;
hemophilus influenzae;
enterobacteria;
shigella;
Klebsiella etc.

The principle of its action is quite simple - the active substance destroys the cell walls of bacteria. This not only prevents their further reproduction, but also leads to death. The antibiotic is distinguished by its rapid action. When administered intramuscularly, the concentration of the active substance in the blood reaches its maximum value in just 1.5 hours. In this case, the medicine completely works for the benefit of the body, since its bioavailability is 100%.

The antibiotic is excreted from the animal’s body mostly through the kidneys along with urine and only partially through the intestines with bile.

Interaction with medications

When Cefotaxime is combined with loop diuretics, a nephrotoxic effect develops. When using an antibiotic simultaneously with nonsteroidal anti-inflammatory drugs and antiplatelet agents, internal bleeding occurs.

If taking an antibiotic coincides with therapy with antithrombotic drugs, the risk of bleeding increases several times.

Its use is also not advisable if the patient is already receiving therapy with aminoglycosides or polymyxin.

B or loop diuretics, since such a tandem often causes renal failure.

How to use the drug correctly

Cefotaxime in the form of injections is used both intravenously and intramuscularly. The instructions indicate that the antibiotic can be used for both adults and children. If the patient develops diseases that are uncomplicated, the drug is administered intramuscularly or intravenously as a dropper.

For the development of moderately severe infectious diseases, Cefotaxime is used 2 g 4-6 times a day. The dosage is prescribed by your doctor, so it may vary. The duration of the course is also prescribed by the doctor depending on the nature of the disease. Before surgery, the drug is administered intravenously or intramuscularly, which will eliminate infection. If necessary, the drug can be reused.

For children, Cefotaxime is prescribed by the attending physician, and the dosage depends on the weight and age of the child. For newborn babies, the dosage of the drug does not exceed 50 mg/kg body weight 2 times a day. Children from 7 days to a month are prescribed the drug in an amount of 50 mg/kg every 7-8 hours. If the child is over 2 years old, the drug is administered at a dose of 50-180 mg/kg 4 to 6 times a day. If complications occur in a young patient, the dosage may be increased. The duration of therapy is influenced by factors such as the nature of the disease. Often the course lasts from 7 to 14 days. For children under 2 years of age, the drug should be administered intravenously only.

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Ceftriaxone is a third-generation drug from the “Cephalosporins” group of antibiotics. Ceftriaxone is an inexpensive, effective and quite popular drug in veterinary practice.
The antibiotic is prescribed for a huge number of diseases, it relieves inflammation well, the drug is strong, with a wide spectrum of action.

Ceftriaxone is prescribed for 7-10 days. The drug is taken 1 time per day.

Usually the drug is stopped three days after the temperature has normalized and all symptoms have disappeared. It is extremely important to complete the entire course of treatment and not interrupt it when the animal’s condition improves.

The drug begins to act 2-3 hours after administration; to achieve results, you must complete the full course, even when the symptoms of the disease have disappeared. However, if after 3-5 days there is no improvement, and even more so if the condition worsens, you should immediately contact a veterinarian.

The injections are painful, so we will dilute the drug with novocaine 0.5%. It is possible to use lidocaine, but when using it, allergic reactions, heart and breathing problems are possible! Water for injection is also acceptable, but the animal will experience severe pain. Therefore, Novocain 0.5% is the best option.

Add 5 ml Novocaine 0.5% into a bottle of ceftriaxone (1 g).
Mix well, the solution should become homogeneous and yellow in color.
We fill the syringe with the required amount of medicine, usually 1-1.5 ml per 5 kg of animal weight. Read below for the exact dosage.
We dispose of the bottle with the remaining medicine; it cannot be stored!

The dosage is determined based on the weight of the animal. 20-40 mg of antibiotic is administered per 1 kg

For cats and dogs weighing less than 2 kg - 0.5 of the prepared solution.
For cats and dogs weighing about 3-4 kg, 1 ml of the finished medicine is prescribed.
For cats and dogs weighing more than 4 kg, the dosage is increased, so for a cat weighing 4.5 kg, the dosage will be 1.3 ml of the finished medicine. (provided that the powder was diluted with 5 ml of novocaine 0.5%)

Overdose is dangerous. The exact dosage is prescribed by the attending physician. However, if there is no opportunity to see a doctor, then the average dosage is 1 ml of a ready-made, properly diluted drug per 5 kg of animal weight.

Ceftriaxone is injected into the muscle of the hind paw, alternating paws.

We administer the medicine slowly.

If Ceftriaxone does not get into the muscle, but the injection is administered, nothing needs to be changed. We give the next injection exactly one day later. If ceftriaxone is accidentally injected into the withers, the actions are exactly the same, nothing bad will happen, monitor the pet’s condition, don’t worry. And there is no need to redo the injection, the animal has received the drug. However, in the future you should be careful and inject the medicine into the muscle!

Remember that the drug must be prescribed by a doctor. And the dosage and course of treatment are determined individually in each specific situation. The above recommendations were received from a veterinarian, but do not replace an in-person consultation, examination of the animal and tests.

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Source treimut.ru

Under certain circumstances, the use of medications is indicated in veterinary medicine. An antibiotic of the third generation of cephalosporins, Ceftriaxone has a wide range of effects on the microbial community. This article provides instructions for the use of the antimicrobial drug Ceftriaxone in veterinary medicine. Informs animal lovers of situations that require the use of this particular drug.

Dispensing form: cardboard packages of ten glass bottles containing 1 g of powder for parenteral administration.

Ceftriaxone for dogs - reviews

Review of ceftriaxone for dogs, writes Liliya. After my dog underwent surgery, the veterinarian prescribed Ceftriaxone, warning us that it should only be mixed with Novocaine.

It was necessary to inject for 7 days at a dosage of 1g per day. We performed intramuscular injections into the hind paw. We were warned that the injections would be painful for the dog, but she behaved calmly.

Ceftriaxone price

Ceftriaxone 1g in a bottle – from 640 rubles.

Storage conditions

Store at a temperature of 15 to 25 degrees Celsius, out of direct sunlight and out of reach of children.

Ceftriaxone price

Storage conditions

In what cases is Cefotaxime contraindicated?

Injections of the drug are contraindicated for:

Intolerance to Cefotaxime, the occurrence of allergic manifestations;
First trimester of pregnancy;
Bleeding;
Enterocolitis;
The presence of acute colitis.

The medicine is used with caution in the treatment of newborns and patients with severe pathologies of the liver and kidneys.

Use during pregnancy and breastfeeding

For pregnant women, Cefotaxime injections are prescribed for the presence of various infections in the second and third trimesters of pregnancy. In the first case, the use of the medicine is strictly prohibited, since during this period all the vital organs of the fetus are formed.

If injections are prescribed to a nursing mother, then she should stop breastfeeding.

Pregnant women are allowed to use the drug only strictly as prescribed by the treating doctor and under his supervision.

Use of Cefotaxime in childhood

As mentioned above, Cefotaxime injections can be used in the treatment of even infants, but it is worth remembering that the drug lingers longer in a child’s body than in an adult, so treatment should be carried out with great caution and strictly under the supervision of a pediatrician. Under no circumstances should you self-medicate. Especially when it comes to your infant.

Antibiotic JSC "Sintez" Ceftriaxone - review

I have already talked about our wonderful cat, whom I found on the street, dirty, crazy, covered in garbage. She had a whole bunch of infections and had to be treated for a very long time. And, as it turned out, very often animals are treated with human medicines. My cat's veterinarian prescribed injections of the antibiotic ceftriaxone, which is sold in a regular pharmacy, since it is a drug for humans. But it can also be used in a certain dosage for infants, so it is also used for cats. It is very inexpensive and easy to buy. But I had a lot of questions that I was tired of looking for answers to, so I’ll try to help you: how and in what way to dilute ceftriaxone for cats? How long can the prepared ceftriaxone solution be stored? What and where to inject a cat with an antibiotic? How to give a cat an injection at home yourself? I will try to tell you all about this in detail.

Michaella had sinusitis, and it was very terrible.

These are the sniffles the cat had. She had snot running with blood from her nose, and she could not breathe through her nose at all. This is how my nose was covered with a crust of blood and snot while I was at work. This is what Mikaella looked like after washing. The kitty felt terrible, she could neither eat nor walk. She was just lying there. Therefore, we decided to give the injections at home ourselves, since the doctor in our small town does not come to our home.

Ceftriaxone dosage for cats

First, you need to calculate the dosage based on your pet's weight. The doctor prescribed us 10 mg per kilogram of the cat’s weight 2 times a day intramuscularly for 10 days. When I got home, I stood on the scales with the cat and then without the cat, and calculated that our little one weighed only 3 kg, which meant that the injection needed to be 30 mg. And a bottle of ceftriaxone contains as much as 1000 mg. In general, this was the first difficult moment.

Ceftriaxone bottle 1 g

What and how to dilute ceftriaxone for cats

As you can see, ceftriaxone is a powder; in order to inject it into an animal, it must be diluted. People dilute it in different solutions, but the veterinarian told the cat to dilute it strictly in novocaine. I bought a package of 10 ampoules of novocaine 0.5%, each 5 milliliters, at the pharmacy. You will also definitely need a syringe of the same volume as the ampoule of novocaine that you will take. (They come in 2 ml, 5 ml and, it seems, even 10 ml). I recommend taking 5, as this is the most convenient volume for dilution. 2 ml is too little, it is more difficult to dissolve the powder. And 10 ml will not fit into the bottle. And you will need new syringes when opening each ampoule of novocaine and preparing the ceftriaxone solution, since the syringe must be sterile so as not to infect the cat again.

So, break the ampoule of novocaine and fill the syringe with the solution. Remove the metal cap from the ceftriaxone bottle

This piece of iron needs to be torn off and all the novocaine must be injected into the rubber stopper with a syringe. Then you need to shake well and voila - the solution is ready. Next, you need to remember the math and calculate how much solution you need to put into the syringe to inject your cat. My little one needs 30 mg. And in a 5 ml solution there is 1 gram or 1000 mg. Let's make a proportion:

30 mg - x ml

1000 mg - 5 ml

It turns out that the cat needs to be injected with 30*5/1000 = 0.15 ml of solution.

How to give an intramuscular injection to a cat.

An intramuscular injection is most often given to a cat under the hind leg. You know, a chicken thigh is where the meat is, that’s where you need to inject your cat.

This is approximately where you need to give an intramuscular injection to a cat

You need to inject with needles from insulin syringes, they are much thinner. Believe me, there is a difference. At first I injected with two-cc syringes, and it was very painful for the cat. She meowed a lot. And when I bought insulin, it was heaven and earth. The cat began to tolerate the injections much easier. Do not torture the animal - take insulin syringes immediately. In the same way - one syringe per injection, do not use a syringe or needle twice. Another problem arises - the solution must be drawn from the bottle into a syringe, but when the needle pierces the bottle, it becomes very dull and it is no longer possible to inject it. Therefore, I did this: I prepared a solution with a 5-cc syringe, then took an insulin, removed the needle from it, put on a needle from the 5 and drew 0.15 ml of the solution. Then she threw away this needle, put on an insulin needle and gave an injection with a new needle. Make sure that the pharmacy gives you insulin with removable needles. Otherwise they gave me one with non-removable ones. That's how they lie.

This is what an insulin syringe with a non-removable needle looks like

The most convenient way to inject a cat is in a position where she lies on her paws, with her back leg stretched out with your hand. Just like in the photo we hold it and prick it.

We yawn while taking photographs;) We tried to wrap the cat, but this only made her even more nervous and pulled away. If you have a very small cat like I do, be careful not to poke all the way through the cat or poke air instead of the cat. Oh yes, and release any air bubbles from the syringe. Cats have small muscles, and they are really easy to pierce through. The injection must be given slowly but surely. And everything will not be as scary as it seems. After giving the injection, you need to massage the muscle with your fingers so that the medicine is evenly distributed and the pain is reduced. The first time after the injection, the cat's leg may hurt and it may even limp. This is an adverse reaction. It will pass quickly. But the legs of the injection need to be alternated to reduce pain.

How long to store ceftriaxone solution.

As the instructions say:

the solution must be used freshly prepared

that is, for each injection you need to make the solution again. According to the manufacturer's description, the solution remains sufficiently stable for 12 hours when stored in the refrigerator.

But you will see for yourself that it changes over time - the solution turns yellow and begins to smell bad. Surprisingly, the ceftriaxone solution smells, excuse me, like urine. And my husband and I thought that Mikaella peed herself out of fear, but it turned out that I poured a little bit of the solution from the syringe to release air bubbles and it stank.

I still advise you to make a new solution each time, because for a cat the injection is already very painful. Is it really worth subjecting a cat to such torture if the effectiveness of the medicine has already decreased significantly over time? Moreover, this drug is very inexpensive, a little more than 20 rubles per bottle.

The cat felt better already on the second or third day. And then the baby gradually recovered. We are very happy.

Cheerful healthy cat stretches and plays with her favorite tinsel

Hello! Well, for starters, injecting furosemide and taking blood tests the next day is wrong, since furosemide removes a large amount of fluid from the body and from the bloodstream, respectively, too, thereby thickening the blood, this in turn artificially changes the blood picture, since the volume of fluid first it falls, then the animal becomes very thirsty and begins to greedily drink water, trying to restore the required amount of fluid in the body again. Now, according to the actual analysis, leukocytosis is indeed pronounced, which can be the cause of both a viral disease and an oncological one. I am on the side of the doctor who advised you to first undergo all the necessary tests, because it would not be bad to see the detailed biochemistry of the blood. As for treatment: prescribing furosemide is a very responsible step, the doctor himself decides whether to do it or not; in my opinion, it should be prescribed only in extreme cases when there is either a real risk to the animal’s life and a quick effect is required, or it is not possible to remove the liquid in any other way. It should also be taken into account that furosemide will be effective only when you limit the animal’s water, since if the animal drinks freely, it will quickly restore the lost fluid and the swelling will not go away. Also take into account that potassium furosemide is not a sparing diuretic, so it is prescribed, as a rule, with asparkam (the drug restores the amount of potassium and magnesium ions in the blood); without this drug (or its analogue), heart problems may begin. Further, the kitten had a good reaction to treatment according to the antiviral, immunostimulating, antibiotic regimen (imunofan, anandin, Vitafel C, ceftriaxone), but 3 days is not enough to treat a viral disease that causes such complications, so I would advise extending the treatment regimen to 10 -14 days. Of course, it’s difficult for me to judge, but I would prefer a few other drugs: - Imunofan 1 injection after 3 days (5 injections in total) - Anandin must be injected for at least 5 days, and in your case (if there is an improvement in the animal’s condition) I extended it to at least 10 days - Gamavit 1.5-2.0 ml 1 time per day, this will cause a correction of the immune response and will also have a beneficial effect on anemia (which is noted according to the analysis) - Vitafel-S its greatest effect is achieved in the first days of the onset of the disease, but you can leave it .. And even if you injected this drug, you cannot vaccinate the animal for 14 days, since the antibodies contained in the drug will kill the vaccine strains of the virus in the vaccine and the development of immunity will not occur. — I would change Ceftriaxone to another broad-spectrum antibiotic, since its side effects, although in rare cases, can cause anemia, leukocytosis, etc. Regarding the a/b (antibiotic) against bacteria, they are all the same at this stage. Regarding worming - it all depends on the drug, if the doctor prescribes a mild drug, then you can use it now, but you must have clear reasons for its use, that is, the helminths must be either those that can cause similar symptoms in the animal, or helminths in There is a lot of gastrointestinal tract (gastrointestinal tract). Regarding fluid, if the animal’s condition improves after continuing treatment, then you are treating correctly, eliminate the cause of the disease - the excess fluid will also go away. Regarding whether it is possible to vaccinate without worming, in general it is possible, but in this case, until the animal is healthy, vaccinating it is simply dangerous (to the point of death).

How to inject cefotaxime into a cat

Is it possible to store a diluted drug?

Unopened vials of Cefotaxime have a shelf life of 2 years. For a diluted drug stored in a bottle with a closed stopper, the shelf life is reduced by 730 times. This means that diluted Cefotaxime can be stored for no more than a day. In this case, the vessel should be in a cool and dark place.

Drugs that need to be prepared for use in injections require special attention. Even under the best conditions, they lose their healing properties soon after opening the hermetically sealed container. When using injection products, solutions should not be stored in ampoules with broken packaging for more than 12-20 hours. This rule applies to all types of antibiotics.