Mechanism of action of the drug
The mechanism of action of Sinulox is based on the properties of its active components.
The product contains two active ingredients: the main one is amoxicillin, and the additional one is clavulanic acid. The first blocks the activity of bacterial enzymes, which leads to the destruction of their cell membranes and the death of microbes. Some bacteria are capable of producing a substance that destroys the antibiotic even before it takes effect. To prevent this from happening, the manufacturer added clavulanic acid to Sinulox. It inhibits the activity of the enzyme, protecting amoxicillin from destruction and providing the therapeutic effect of the drug.
Properties, composition and release forms of the drug
Sinulox is an antibacterial agent of the penicillin group. Penicillin was invented in the early 19th century by the scientist Fleming. The discovery of this antimicrobial compound allowed medicine to take a big step forward. Many infectious diseases that used to be a threat to humanity have become easily treatable.
The trade name of the drug is Synulox. Veterinarians prescribe this new generation remedy to sick cats and dogs, as well as cattle.
Its formula was developed by American representatives in the city of New Jersey. The company's representative offices are open all over the world in different cities, including Moscow. The same medicine is produced by the Italian company. The packages of tablets contain appropriate manufacturer's marks.
The medicine is available in the form of tablets of 50, 250 and 500 mg, packaged in soft blisters containing information about the mass fraction of the active component in the drug, batch and expiration date. Blisters are folded into small cardboard packages of 2–5 pieces, depending on the dosage. The tablets themselves are pinkish with a line-shaped indentation in the center. When broken, white crystals are visible on the surface of the tablet.
The box usually has a picture of a dog or cat on it. The name of the medicine must be indicated in two languages, information about the number of tablets and dosage is given. Newly produced Sinulox boxes have a design in the form of curved stripes of yellow and pink colors.
The product is also available in the form of a suspension for injection use. It is a cloudy liquid with an oily consistency, packaged in pink glass bottles. The bottles are closed on top with a rubber stopper and sealed with an aluminum seal. There are two packaging options for the drug - 6 bottles with a capacity of 100 ml or 12 bottles with a capacity of 40 ml.
Each bottle is affixed with a label with the trade name of the drug and the company logo, as well as a design - two stripes of yellow and pink. The expiration date and release date are also indicated.
The drug contains two components - amoxicillin trihydrate and clavulanic acid. Thanks to this, Sinulox has a wide spectrum of action against different microorganisms and their strains. It is capable of destroying gram-negative (Bordetella bronchiseptica, Salmonella, Proteus spp., etc.) and gram-positive (staphylococci, streptococci, etc.) bacteria.
When is Sinulox prescribed?
Indications for the use of the antibiotic Sinulox may include the following disorders in cats caused by microorganisms:
- purulent inflammatory processes on the skin (pyodermitis and others);
- diseases of the urinary and reproductive systems (endometritis, cystitis);
- pathologies of the mucous membranes and soft tissues of the oral cavity (for example, stomatitis);
- infectious processes developing after injury, surgical procedures;
- diseases of bacterial origin in newborn kittens;
- diseases of the respiratory system (pneumonia, rhinitis and others).
Indications for use
Attention! Before use, consult a specialist.
The drug Sinulox is indicated for dogs for many infections of bacterial etiology. The product is especially popular for the treatment of infectious infections of the skin, mucous membranes of internal organs, excretory, reproductive and respiratory systems. In veterinary medicine it is prescribed for the following diseases:
- stomatitis;
- bacterial cystitis;
- tonsillitis;
- mild forms of enteritis;
- benign neoplasms;
- pneumonia, pleurisy.
Sometimes the drug Sinulox is recommended for use after surgery, removal of certain types of tumors. Amoxicillin in the composition is suitable for complex therapy together with anti-inflammatory and wound healing agents.
How to use Synulox
The use of Synulox for the treatment of cat diseases must be carried out in strict accordance with the instructions for use. When selecting a specific dose and form of the drug, the veterinarian takes into account not only the weight of the animal, but also assesses its condition, the likelihood of possible complications, the degree of development of the infectious process and other parameters, therefore spontaneous “treatment” based only on weight indicators can lead to deterioration of the cat's condition.
During treatment with tablets, as well as when giving injections, you should not skip the next dose (injection) of the drug. This can not only reduce the effort expended to zero, but also lead to bacteria becoming unresponsive to the antibiotic, weakening the animal’s body, and contributing to the worsening of inflammatory processes. If for some reason you manage to miss one dose of the medication, and there is still time to do so, then it should be done as quickly as possible. If the time has already come for administering the next dose of the drug, then it is administered without taking into account the omission, that is, the dosage does not need to be doubled.
What to choose: tablets or injections
It is impossible to answer this question unequivocally, since the choice of the form of the drug depends on the condition of the dog. If the disease is mild or moderate in severity, and the gastrointestinal tract allows you to take tablet form, then taking Sinulox tablets is quite possible. If your pet is seriously ill with the infection, the disease is accompanied by complications, the tablets lead to vomiting and are not absorbed, injections are the best treatment option. A medicine injected into muscle or connective tissue is immediately absorbed into the bloodstream and leads to a rapid therapeutic effect.
Instructions for use of tablets
Sinulox tablets
According to the instructions, the tablet form of Sinulox is given to cats twice a day, regardless of food. The tablet can be given simply by hand or pre-crushed and added to food during feeding. It is important to ensure that your pet eats the entire portion of food without leaving any leftovers, otherwise the effectiveness of treatment will be low. Another option for tablet therapy is to crush the tablets, mix them with water in a teaspoon, and then pour them into the cat’s mouth, holding the jaws so that the solution does not spill out.
A single dosage of Sinulox is 12.5 mg per 1 kg of cat weight. It is allowed to increase it to a maximum of 25 mg per 1 kg in case of a serious condition of the animal or a high risk of complications and other situations. The duration of therapy is usually 1 week. For infections that are difficult to treat or a chronic course of the disease, the duration of treatment can be increased to two or more weeks.
Sinulox in suspensions
Instructions for use of the suspension
The Sinulox suspension is used in injection form - injections are placed under the skin in the cat's withers or gluteal muscle. The application regimen is as follows: one injection per day for 3-5 days (in some particularly difficult cases, the veterinarian may prescribe longer treatment). After giving the injection, the injection site should be gently massaged.
A single dose of the drug must be pre-calculated. The medicine is taken based on the proportion of 8.75 mg per 1 kg of cat’s body weight. This corresponds to 1 ml of suspension per 20 kg of animal weight. Often owners are faced with the problem of collecting such an amount of the drug, for example, with a small body weight. Experts advise using an insulin syringe.
When injecting Synulox, you must strictly adhere to the following rules:
- the drug cannot be injected into a vein;
- The suspension should be shaken before the injection;
- you only need to draw the suspension with a completely dry needle and a dry syringe.
Features of using medicine for dogs
Despite the versatility of the drug Sinulox, it should be taken only as prescribed by a veterinarian and in accordance with the instructions for use. When choosing the form of medication and dosage, the specialist focuses not only on the weight of the dog - other nuances are also taken into account:
- age;
- state of the immune system;
- concomitant pathologies;
- severity of the disease and others.
If the drug is prescribed incorrectly, the pet's condition may worsen.
The key to the effectiveness of any antibacterial agent is the continuity of the course of treatment. In no case should you skip taking a medication, stop the course ahead of time, or replace one remedy with another without first consulting a specialist. Such actions will increase the resistance of the microorganism to the active ingredients, “implant” the immunity of the four-legged friend, and increase the risk of developing side effects. This applies to both the tablet form of Sinulox and the injection form. If for some reason the next dose of medication is missed, the dose prescribed by the doctor is administered the next time, without resorting to doubling it.
Pills
Sinulox tablets are given to dogs twice a day. They can be taken with food or on an empty stomach. In the first case, there is a risk of a gag reflex, and in the second, taking the medicine can negatively affect the condition of the animal’s stomach.
How to give a pill to a dog is decided by each owner individually. The drug can be mixed into a small amount of food that the pet likes most, placed in the oral cavity, and also used as a tablet dispenser. If the tablet is mixed into food, you need to make sure that it is completely eaten.
The amount of medicine for one dose according to the instructions must be pre-calculated: per 1 kg of dog’s body weight, 12.5 mg of medicine is required. If the animal is very sick, with complications, the specialist may prescribe a higher dosage, but not exceeding 25 mg / 1 kg. The duration of treatment is also calculated individually and can range from 1 to 2-4 weeks.
Injections
Sinulox in the form of a suspension
The duration of the course of Synulox injections is shorter - injections are given from 3 to 5 days. If the animal is in extremely serious condition, the specialist may prescribe a longer course. The frequency of injections per day is once.
Injections can only be given into the dog’s muscle or subcutaneously into the withers area; the product is not suitable for intravenous infusion. The medicine is administered slowly to avoid lumps. For the same purpose, after injection, the injection site of the suspension is lightly massaged.
As with tablets, the dosage must be calculated in advance: per 1 kg of dog weight, take 8.75 mg of Synulox. Or: 1 ml of medicine per 20 kg four-legged patient. In order not to make a mistake with the dose of the drug, you can use an insulin syringe. Before taking the suspension, you need to shake it a little.
Attention: the syringe and needle must be dry! Clavulanic acid, when mixed with water molecules, loses its properties.
Contraindications and side effects
The drug Sinulox has few contraindications: intolerance to the components of the drug and allergies to antibiotics. It is also contraindicated to give Sinulox to cats if at this time they are being treated with bacteriostatic drugs, for example, chloramphenicol.
Side effects are also few in number, and they are observed in rare cases. If the dosage is not observed and in overly sensitive cats, the following reactions may occur:
- skin rashes;
- disorders of the digestive tract (diarrhea, difficulty defecating);
- swelling of the skin or mucous membranes;
- lacrimation.
If such symptoms are detected, the animal should be shown to a veterinarian. Perhaps he will reduce the dosage of the drug or prescribe another remedy. In some cases, the symptoms go away on their own.
Advantages of the drug
The popularity of Synulox is based on its many benefits.
What does a Sinulox tablet look like?
- High efficiency. The use of the drug is indicated even in the case of a chronic, advanced disease or its complicated form. At the same time, the pet’s condition noticeably changes for the better after just a few days from the start of treatment.
- There are almost no contraindications for use. Sinulox can be given to newborn kittens and older animals, as well as weakened pets.
- Well tolerated. Side effects may only occur occasionally.
- Versatility. The antibiotic Sinulox has a pathogenic effect on a large number of strains of microorganisms (gram+ and gram-).
- Does not have a pronounced detrimental effect on beneficial microflora. When used correctly, the drug kills only pathogenic microbes, preserving the animal’s immune system.
- There is a choice: tablets or injections. Sometimes giving an injection to an animal is quite problematic, so you can use the tablet form.
- Easy to use. To give an injection, you do not need to mix the ingredients; the suspension is completely ready for use.
- Purchasing is hassle-free. The drug can be purchased at almost every veterinary pharmacy.
How much does Synulox cost?
The price of the antibiotic Sinulox depends on the form and volume of the product. Thus, 50 mg tablets can be purchased at a cost of 180-200 rubles per pack (10 tablets). The suspension is more expensive - for 40 ml of medicine you need to pay about 1000 rubles, and for 100 ml - more than 2000 rubles. It is worth considering that the bottle can only be stored for one month after taking the suspension from it.
Judging by the reviews, Sinulox is an absolutely safe and very effective treatment for bacterial infections in cats. The main thing is not to give it to your pet without the supervision of a specialist.
