Omez for cats - instructions for use, dosage

Treatment of gastritis in cats

Self-medication and the use of any medications without consulting a veterinarian are fraught with disastrous consequences for the health and life of the cat.

Acute gastritis caused by a single violation in the pet's diet is treated with a starvation diet lasting 24 hours or more on the recommendation of a doctor. Until the animal’s condition normalizes, it is advisable to give only boiled water as drinking water.

After following a starvation diet, the animal is given mucous decoctions of rice or flax seeds. It is forbidden to suddenly return to the cat’s usual diet - this must be done gradually and with caution.

If a cat is vomiting, then use antiemetic drugs:

• Metoclopramide (0.2-0.4 mg per kilogram of animal weight subcutaneously or orally 3 times a day);
• Zofran or Ondansetron (0.5 mg per 1 kg of animal weight 2 times a day intravenously or orally);
• Anzemet or Dolasetron (given orally (by mouth) or intravenously at 0.5 mg per 1 kg of animal weight once a day);
• No-shpu and Cerucal are used with caution; there are contraindications (subcutaneously at the rate of 0.1 ml per 1 kg of cat weight no more than 1-2 times a day).

For vomiting with increased acidity of gastric juice, the following is prescribed:

• Famotidine (0.5-1 mg per 1 kg of animal weight subcutaneously, intravenously 1-2 times a day);
• Ranitidine (tablets 3.5 mg per 1 kg of weight 2 times a day; solution administered intravenously 2.5 mg per 1 kg of weight 2 times a day);
• Omeprazole (0.5 mg per 1 kg of weight no more than 1 time per day orally).

Also, in case of high acidity, enveloping drugs are used, such as Phosphalugel, Almagel.

If the acidity is low, the cat is given cabbage or beet juice.

To eliminate stomach upset, animals are given a decoction of oak bark or St. John's wort. For medicines, crushed activated carbon is given, Atoxil is mixed with boiled water.

If gastritis in cats is of a bacterial nature, antibiotics can be prescribed, but their use is advisable only as prescribed by a doctor.

In case of particularly severe intoxication of the body, in case of dehydration - infusion therapy to flood the body and remove toxins.

If your animal exhibits any of these symptoms, you should immediately go to the veterinarian's office. There the doctor will conduct an examination that will answer the question about her health.

Gastritis is usually treated by fasting for a day. However, you can’t do without tablets and capsules. The doctor will prescribe the right medicine and tell you how to give Omeprazole. Then the cat is prescribed a diet. The pet should eat rice water and flaxseeds. The cat should take a decoction of crushed oak bark along with Omeprazole, but you can also take a decoction of St. John's wort.

Only a veterinarian can prescribe the correct use of the medicine. The dosage of Omeprazole for cats is very important. Typically, 0.5 mg of the substance is given per 1 kg of weight, once a day by mouth. However, it is necessary to check with the pharmacist; the instructions for use of Omeprazole for cats are the best way to study the medicine.

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Doses of omeprazole for cats:

• For the treatment of ulcers in cats, omeprazole is used at a dose of 0.7 mg/kg per os once a day
  (Johnson 1996).

No studies have examined the potential side effects for chronic use of omeprazole in cats. Therefore, researchers from the University of Tennessee College of Veterinary Medicine and colleagues assessed the effect of chronic oral administration of omeprazole on serum concentrations of calcium, magnesium, cobalamin and gastrin, as well as on mineral density and bone content in cats. An additional smaller subgroup of cats were assessed for signs of RAH following abrupt cessation of omeprazole therapy.

In this study, six healthy older adult cats (≥7 years) received placebo before and after treatment, followed by omeprazole for 60 days each.

Serum calcium, magnesium, cobalamin, and gastrin concentrations were measured on days 0, 30, and 60. Bone density and content were assessed on days 0 and 60 of each intervention. On day 60 of omeprazole administration, pH capsules were attached to the stomachs of two cats, and continuous intragastric pH monitoring was performed to evaluate the effects of sudden withdrawal of omeprazole.

In conclusion, no cats had statistically significant decreases in serum concentrations of magnesium, calcium, cobalamin, methylmalonic acid (increased in cobalamin deficiency), bone mineral content, and bone mineral density after 30 or 60 days of omeprazole treatment.

Although the sample size was small, the results of this pilot study suggest that oral omeprazole is relatively safe in healthy cats in courses of ≤8 weeks. In addition, increased gastric acidity was observed in both cats in which intragastric pH monitoring was performed after abrupt cessation of omeprazole.

However, please do not give your cat omeprazole without veterinary intervention.

Possible restrictions and side effects

The official instructions for use describe the following conditions, in the presence of which it is better not to give Omez to a cat:

• personal sensitivity to the components of the drug;
• liver diseases;
• lactation period and pregnancy.

In some cases, after such therapy the pet becomes aggressive.

• urge to vomit;
• angioedema, anaphylactic shock;
• aggressiveness;
• confusion;
• headache, vertigo;
• drowsiness, malaise;
• violation of taste preferences;
• deterioration of visual function;
• bronchospasm;
• dry mouth;
• painful discomfort in the abdomen;
• stool disorders;
• muscle weakness;
• swelling of the lower extremities.

Indications for use

There are several diseases for which cats should take Omez. The most common among them are:

• acute and chronic ulcers;
• pancreatitis;
• mastocytosis and others.

It is very important that the veterinarian conduct a preliminary diagnosis before prescribing Omez to the cat. Only in this case can the high chance of side effects and personal intolerance be eliminated. If any allergic reactions occur, you should immediately stop using Omez. It can be replaced with another remedy, for example, Kvamatel.

Contraindications

It is important to take into account some contraindications that are especially characteristic of this medication. Treatment of a cat with Omez is not recommended for:

• the presence of personal sensitivity to omeprazole;
• liver pathologies;
• taking a course with drugs that are incompatible with Omez;
• in cats - during pregnancy and lactation.

All of these factors must be assessed by a veterinarian. If any signs of overdose occur or there are any side effects, for example, vomiting, you should stop using the drug for your pet.

Omeprazole overdose/Acute toxicity

• The LD50 in rats after oral administration of omeprazole is known to be >4 g/kg. In humane medicine, there are cases where patients tolerated doses of 360 mg/day without signs of significant toxicity.
• If excessive overdose occurs, symptomatic and supportive treatment should be prescribed.
• Drug interactions: Because omeprazole can inhibit the cytochrome P-450 enzyme system, it may reduce the hepatic clearance of diazepam (Sibazone), phenytoin or warfarin, thereby increasing their effects and causing toxicity. In this case, additional monitoring and dose adjustment of the drug is required.

Omeprazole may increase gastric pH and therefore reduce the absorption of drugs that require a low pH for optimal absorption (eg, ketoconazole, ampicillin esters or iron salts).

In humane medicine, there is evidence of rare cases of bone marrow suppression, so the simultaneous use of omeprazole with drugs that can also cause bone marrow suppression may lead to the development of additive hematological disorders.

Effect on laboratory parameters Omeprazole may cause an increase in liver enzymes. At the beginning of treatment, the drug increases the level of gastrin in the blood serum.

According to the instructions for use in cats, omeprazole is often the first choice acid suppressant.

This remedy is prescribed to cats with diseases that can lead to increased stomach acidity, ulcerative esophagitis, gastritis or gastrointestinal (GI) bleeding.

However, in humans, long-term use of omeprazole can lead to serious side effects, including an increased risk of community-acquired pneumonia and Clostridium difficile infections, adverse drug interactions, cobalamin (vitamin B12) deficiency and calcium and magnesium imbalance with subsequent development of osteoporosis and pathological fractures. In addition, a phenomenon known as ribonic acid hypersecretion (RAH) has been shown to occur after sudden cessation of omeprazole during long-term treatment.

Side effects of omeprazole / Warnings for use in cats

Veterinary practice with the use of omeprazole is limited, but despite this, it is known that the drug is quite well tolerated by cats when given effective doses. There is a possibility of developing disorders of the gastrointestinal tract (anorexia, colic, nausea, vomiting, flatulence, diarrhea), central nervous system, hematopoietic system (there are rare cases in humane medicine), urinary tract infections and proteinuria. Long-term administration of very high doses to rats led to the appearance of perochromaffin-like cell hyperplasia and gastric carcinoid tumors; these negative effects are dose-dependent. The clinical significance of these possible effects in relation to long-term use of the drug at low doses is unclear. However, today in humane medicine long-term (more than 8 weeks) administration of omeprazole is not recommended, unless the effectiveness of treatment prevails over possible side effects.

Dosage for cats

It is not surprising that many owners are concerned about how to give Omez to a cat. Few animals will agree to voluntarily take medication. The method of administration depends on the form of the medicine. For example, the capsule can be mixed with soft food. But you need to prepare a suspension from the powder and forcefully pour it in. As for tablets, they are most often crushed and mixed with food or water.

Storage Features

Omez for cats will retain its positive properties only if stored correctly. The main thing is to put the medicine in a dark, dry place. Permissible temperature – up to +25 degrees

It is important to ensure that children and animals do not have access to the medication. It should also not be stored near food.

When using Omez for pets, you should understand that the medicine can either help or harm the cat. Therefore, you must strictly follow the veterinarian’s instructions and the information on the packaging. Only in this case will therapy bring the desired result.

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How to store?

https://www.youtube.com/watch?v=L7w_f3O6UBI

The preservation of its therapeutic effects until the end of the shelf life depends on the correct storage of the drug. Therefore, the Omez package should be placed in a dark, dry place where the air temperature does not rise above 25 degrees Celsius. Small children and animals should not have access to the medicine, and tablets and powder should not be placed near food. The shelf life is 3 years, after which the use of Omez is strictly contraindicated.

Omez indications for use

To find out about the drug Omez (see photo below) - the indications for its use are wide - you should consult a doctor for a full examination. It is advisable to perform an endoscopy of the stomach and duodenum to identify abnormalities or the initial stage of cancer. This is due to the fact that the medicine can hide the symptoms of cancer, so treatment with it can make it difficult to make a diagnosis.

Find out about the drug Omez - what the substance is used for according to the annotation. Indications:

• with stomach and duodenal ulcers and their exacerbations;
• erosion of the walls of the stomach;
• peptic ulcers that arise from taking non-steroidal drugs that prevent inflammation;
• ulcers caused by stress;
• Zollinger-Elisson syndrome;
• erosion of the upper stomach and esophagus with cirrhosis of the liver;
• an infection that has destroyed beneficial bacteria in the stomach lining;
• treatment of gastritis and heartburn.

When is Omez used?

1Use of the substance Omeprazole Orally, intravenously. Adult patients: duodenal ulcer; prevention of relapse of duodenal ulcer; stomach ulcer; prevention of recurrence of stomach ulcers; erosive and ulcerative lesions of the stomach and duodenum associated with Helicobacter pylori (as part of complex therapy); erosive and ulcerative lesions of the stomach and duodenum associated with taking NSAIDs; prevention of erosive and ulcerative lesions of the stomach and duodenum associated with taking NSAIDs, prevention of stress ulcers; reflux esophagitis; long-term monitoring of patients with cured reflux esophagitis; gastroesophageal reflux disease; Zollinger-Ellison syndrome.

Application in pediatrics. Inside. Children over 2 years old with body weight ≥20 kg: reflux esophagitis; gastroesophageal reflux disease (heartburn and sour belching). Children and adolescents over 4 years of age: duodenal ulcer associated with Helicobacter pylori (as part of complex therapy).

What is Omez prescribed for and how to take it

Today, advertising is replete with all kinds of medicines existing on the Russian market, for all ailments. It is difficult for an uninitiated person who does not have certain knowledge to understand this flow of information.

Omez, a remedy that is said to effectively treat stomach ailments, was no exception.

Let's try to figure out what kind of medicine this is, why it is prescribed, the properties of the drug, what it helps with, how it is taken, whether it is possible to give capsules and powders to a dog (cat), whether there are cheaper analogues, and other issues.

Composition, release form

Omez (in Latin OMEZ) is an antiulcer drug, the main active ingredient of which omeprazole has a restorative and stimulating effect on the walls of the stomach and duodenum. The product also contains excipients such as mannitol, lactose, sucrose, hypromellose and others. The form of release of the drug is different:

• Instantly coated tablets;
• Capsules, highly soluble under the influence of gastric juice;
• Powder recommended for dissolution in a certain amount of liquid before use;
• Solution for injection - used intravenously;
• Special drops.

The manufacturer of the product is India, more detailed information about which can be found on the online resource Wikipedia.

Indications for use of the drug Omez

Let's figure out why Omez is prescribed? The main indications for use of the drug are:

• Stomach ulcer;
• Gastritis (acute and chronic);
• Erosion of the gastrointestinal tract;
• Oncological diseases;

The medicine is used effectively for heartburn, pancreatitis, and low acidity of the gastrointestinal tract. It is also indicated for the treatment of Zollinger-Ellison syndrome.

Omez: instructions for use

You can take the drug correctly only as prescribed by your attending physician and in accordance with the dosage indicated in the prescription. Omez is usually prescribed in a daily dose not exceeding 20 mg.

For gastritis, stomach ulcers, heartburn, erosion, poisoning, oncology, it is better to drink it in the morning, in the first half of the day before meals; a method other than this can only be prescribed by a specialist.

The course of treatment is also determined by the doctor - gastroenterologist or therapist; as a rule, it is about 2 weeks (14 days). Alcohol is strictly contraindicated during this period.

It is not recommended to give the substance to a dog or cat, since it is not used in veterinary practice.

During pregnancy, how to take?

During pregnancy, the drug is definitely contraindicated, especially in the early stages. It should also not be used while breastfeeding.

If you have gastritis, should you take Omez before or after meals?

How long can you take Omez without a break? The time course of treatment with this drug is determined by your doctor. And to the question of how long you can take it without a break, the answer should be given by a specialist and expert in the medical field. Typically this continuous period does not exceed 14 days.

Analogs

Today, pharmacies offer the consumer all kinds of substitutes - analogues of the Indian product (in everyday life they are called synonyms), including Swiss, German manufacturers, as well as those made in Russia.

Domestic analogues, by the way, are very popular, since the composition differs slightly, and the cost is much lower, which plays an important role for the local consumer.

Such drugs of this pharmacological group include specimens from the list:

• Ranitidine;
• Omeprazole;
• Losek Maps;
• Ranitidine;
• Nolpaza;
• Omezol;
• Ultop;
• Orthanol;
• Nexium;
• Famotidine;
• Emanera;
• Control;
• Almagel;
• Kvamatel;
• Maalox;
• Duspatalin;
• Phosphalugel.

Searching for cheaper analogues is not always the right decision, especially if the doctor himself prescribed a particular medication.

The difference may seem insignificant to you, but a substitution in one or two components of the composition will be significant for the body.

As for the price, it is necessary to immediately indicate the amount for which you can afford treatment. And then the question related to cheaper medications will not arise for you after leaving the specialist.

Source

Omez Omeprazole instructions for use

1Characteristics of the substance Omeprazole Omeprazole is a racemic mixture of two enantiomers. White or off-white crystalline powder, highly soluble in ethanol and methanol, slightly soluble in acetone and isopropanol, very slightly soluble in water. It is a weak base, its stability depends on pH: it undergoes rapid degradation in an acidic environment, relatively stable in an alkaline environment. Molecular weight - 713.12. Pharmacology Pharmacological action - antiulcer, proton pump inhibitor. Pharmacodynamics Mechanism of action Omeprazole is a weak base, concentrated and converted into the active form in the acidic environment of the secretory tubules of the parietal cells of the gastric mucosa, where it inhibits the enzyme H+, K+-ATPase (proton pump). Omeprazole has a dose-dependent effect on the final stage of hydrochloric acid synthesis and inhibits both basal and stimulated acid secretion in the stomach, regardless of the nature of the stimulus. Effect on gastric secretion Omeprazole, when taken orally daily, provides rapid and effective inhibition of daytime and nighttime hydrochloric acid secretion. The maximum effect is achieved within 4 days of treatment. In patients with duodenal ulcers, omeprazole 20 mg causes a sustained reduction in 24-hour gastric acidity by at least 80%. In this case, a decrease in the average Cmax of hydrochloric acid after stimulation with pentagastrin by 70% is achieved within 24 hours. In patients with duodenal ulcers, omeprazole at a dose of 20 mg, when used daily, maintains the acidity value in the intragastric environment at pH≥3 for an average of 17 hours /day IV administration of omeprazole causes a dose-dependent suppression of acid secretion in the human stomach. To achieve a rapid reduction in gastric acidity, intravenous administration of 40 mg of omeprazole is recommended. The antisecretory effect is maintained for 24 hours. The degree of inhibition of hydrochloric acid secretion is proportional to the AUC of omeprazole, but does not depend on its direct concentration in the blood plasma. During therapy with omeprazole, the development of tachyphylaxis was not observed. Effect on Helicobacter pylori Omeprazole has a bactericidal effect on Helicobacter pylori in vitro. Eradication of Helicobacter pylori when using omeprazole in conjunction with antibacterial agents is accompanied by rapid elimination of symptoms, a high degree of healing of defects in the gastrointestinal mucosa and long-term remission of peptic ulcer, which, in turn, reduces the likelihood of developing complications such as bleeding. Pharmacokinetics Absorption Omeprazole, when taken orally, is rapidly absorbed from the gastrointestinal tract, Tmax in plasma is 0.5–1 hour. Omeprazole is absorbed in the small intestine, usually within 3–6 hours. Bioavailability after a single oral dose is approximately 30–40%, after continuous When taken once a day, bioavailability increases to 60%. Food intake does not affect the bioavailability of omeprazole. Distribution The binding of omeprazole to plasma proteins is 95%, Vd - 0.3 l/kg. Biotransformation Omeprazole is completely metabolized in the liver. The main isoenzymes involved in the metabolic process are CYP2C19 and CYP3A4. Given the high degree of affinity of omeprazole for the CYP2C19 isoenzyme, its competitive interaction with other drugs in the metabolism of which this isoenzyme is involved is possible. Hydroxyomeprazole is the main metabolite formed under the action of the CYP2C19 isoenzyme. The resulting metabolites - sulfone and sulfide - do not have a significant effect on the secretion of hydrochloric acid. T1/2 excretion is about 40 minutes (30–90 minutes). About 80% is excreted as metabolites by the kidneys, and the rest through the intestines. Special patient groups Elderly patients (over 75 years of age). In elderly patients, a slight decrease in the metabolism of omeprazole was noted. Renal dysfunction. In patients with impaired renal function, no dose adjustment is required. Liver dysfunction. The metabolism of omeprazole in patients with impaired liver function slows down, leading to an increase in AUC. Omeprazole does not show a tendency to accumulate when administered once a day. Patients with impaired liver function who take omeprazole for a long time may need to reduce its dose. Use of the substance Omeprazole Orally, intravenously. Adult patients: duodenal ulcer; prevention of relapse of duodenal ulcer; stomach ulcer; prevention of recurrence of stomach ulcers; erosive and ulcerative lesions of the stomach and duodenum associated with Helicobacter pylori (as part of complex therapy); erosive and ulcerative lesions of the stomach and duodenum associated with taking NSAIDs; prevention of erosive and ulcerative lesions of the stomach and duodenum associated with taking NSAIDs, prevention of stress ulcers; reflux esophagitis; long-term monitoring of patients with cured reflux esophagitis; gastroesophageal reflux disease; Zollinger-Ellison syndrome. Application in pediatrics. Inside. Children over 2 years old with body weight ≥20 kg: reflux esophagitis; gastroesophageal reflux disease (heartburn and sour belching). Children and adolescents over 4 years of age: duodenal ulcer associated with Helicobacter pylori (as part of complex therapy). Contraindications For oral administration: hypersensitivity to omeprazole; combined use with nelfinavir; children under 2 years of age and weighing <20 kg (in the treatment of reflux esophagitis, symptomatic treatment of heartburn and sour belching in gastroesophageal reflux disease); children under 4 years of age (for the treatment of duodenal ulcer caused by Helicobacter pylori). For intravenous administration: hypersensitivity to omeprazole; combined use with nelfinavir and atazanavir; children's age (up to 18 years). Restrictions on use For oral administration: liver failure; osteoporosis (risk of hip, wrist and spine fractures); simultaneous use with atazanavir (the dose of omeprazole should not exceed 20 mg/day) and clopidogrel; presence of significant weight loss, frequent vomiting, dysphagia, hematemesis, or melena; stomach ulcer (or suspicion of it) - the presence of a malignant neoplasm should be excluded, since treatment can lead to masking of symptoms, etc. delay the correct diagnosis. For intravenous administration: osteoporosis; renal and/or liver failure; history of subacute cutaneous lupus erythematosus; combined use with clopidogrel. Use during pregnancy and breastfeeding Prescription of omeprazole is possible only in cases where the expected benefit to the mother outweighs the potential risk to the fetus. Omeprazole is excreted in breast milk. If it is necessary to use the drug during breastfeeding, it is necessary to decide whether to stop breastfeeding or stop using this drug. Fertility. No effects of omeprazole on fertility have been reported in animal studies. FDA category of effect on the fetus is C. Side effects of the substance Omeprazole Side effects of omeprazole are usually minor and reversible. The following side effects may occur, which are divided into systemic organ classes in accordance with MedDRA. The WHO classification was used to indicate the frequency of side effects: very common (≥10%); often (≥1%, <10%); uncommon (≥0.1%, <1%); rare (≥0.01%, <0.1%); very rare (<0.01%); frequency is unknown (it is not possible to determine the frequency of occurrence of a side effect based on available data). From the blood and lymphatic system: rarely - leukopenia, thrombocytopenia; very rarely - agranulocytosis, pancytopenia. From the immune system: rarely - hypersensitivity reactions (for example, fever, angioedema, anaphylactic reaction/anaphylactic shock). Metabolism and nutrition: rarely - hyponatremia; frequency unknown - hypomagnesemia (severe hypomagnesemia can lead to hypocalcemia); hypomagnesemia may also be associated with hypokalemia. From the mental side: infrequently - insomnia; rarely - agitation, confusion, depression; very rarely - aggression, hallucinations. From the nervous system: often - headache; infrequently - dizziness, paresthesia, drowsiness; rarely - taste disturbance. From the side of the organ of vision: rarely - blurred vision. Irreversible visual impairment has been reported in isolated cases in critically ill patients receiving intravenous omeprazole injections, especially in high doses, but a causal relationship has not been established. From the organ of hearing and labyrinthine disorders: infrequently - dizziness. From the respiratory system, chest and mediastinal organs: rarely - bronchospasm. From the gastrointestinal tract: often - diarrhea, constipation, nausea, vomiting, flatulence, abdominal pain; rarely - dry mouth, stomatitis, gastrointestinal candidiasis, microscopic colitis. From the liver and biliary tract: infrequently - increased activity of liver enzymes; rarely - hepatitis (with or without jaundice); very rarely - liver failure, encephalopathy in patients with liver disease. From the skin and subcutaneous tissues: infrequently - dermatitis, itching, rash, urticaria; rarely - alopecia, photosensitivity; very rarely - erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis; frequency unknown - subacute cutaneous form of lupus erythematosus. From the musculoskeletal and connective tissue side: infrequently - fracture of the hip, wrist bones and vertebrae; rarely - arthralgia, myalgia; very rarely - muscle weakness. From the kidneys and urinary tract: rarely - interstitial nephritis. From the genital organs and breast: very rarely - gynecomastia. General disorders and disorders at the injection site: uncommon - malaise, peripheral edema; rarely - increased sweating. Cases of formation of gastric glandular cysts have been reported during long-term treatment with proton pump inhibitors (resulting from inhibition of hydrochloric acid secretion and is benign and reversible). Interaction The influence of omeprazole on the pharmacokinetics of other drugs Drugs with pH-dependent absorption The absorption of some drugs may change due to reduced acidity of the gastric environment. As with the use of other drugs that suppress the secretion of hydrochloric acid or antacids, treatment with omeprazole may lead to decreased absorption of posaconazole, erlotinib, ketoconazole or itraconazole. Digoxin. With simultaneous use of omeprazole (at a dose of 20 mg/day) and digoxin in healthy volunteers, the bioavailability of digoxin increased by 10%. Digoxin toxicity has been reported in rare cases. However, caution should be exercised when using omeprazole in high doses in the elderly. In this regard, it is necessary to exercise careful therapeutic monitoring of the patient. Clopidogrel. Results from studies in healthy volunteers showed a pharmacokinetic (PK)/pharmacodynamic (PD) interaction between clopidogrel (300 mg loading dose/75 mg daily dose) and omeprazole (80 mg daily), resulting in an average 46% decrease in the AUC of the active metabolite of clopidogrel. and maximum inhibition of ADP-induced platelet aggregation by an average of 16%. Observational and clinical studies have provided conflicting data on the clinical consequences of PK/PD interactions with omeprazole in terms of the development of severe cardiovascular events. As a precaution, the simultaneous use of omeprazole and clopidogrel is not recommended. Nelfinavir, atazanavir. When used simultaneously with omeprazole, the concentration of nelfinavir and atazanavir in the blood plasma decreases. The combined use of omeprazole with nelfinavir is contraindicated (see "Contraindications"). The simultaneous use of atazanavir and omeprazole orally is not recommended; intravenous administration is contraindicated. If the combined use of atazanavir and omeprazole cannot be excluded, it is recommended to carefully monitor the patient clinically and increase the dose of atazanavir to 400 mg using ritonavir at a dose of 100 mg, while the dose of omeprazole should not exceed 20 mg/day. Medicines metabolized by CYP2C19 Since omeprazole is metabolized in the liver by CYP2C19, the elimination of diazepam, warfarin (R-warfarin), cilostazol and phenytoin may be slower. Monitoring of patients taking phenytoin and warfarin is recommended; a dose reduction of the above-mentioned drugs may be required. However, concomitant treatment with omeprazole at a daily dose of 20 mg does not affect the concentration of phenytoin in the blood plasma in patients taking phenytoin for a long time. Concomitant treatment with omeprazole at a daily dose of 20 mg does not lead to a change in coagulation time in patients taking warfarin for a long time. Cilostazol. Omeprazole in doses up to 40 mg in healthy volunteers in a crossover study increased the Cmax and AUC of cilostazol by 18 and 26%, respectively, these figures for one of the active metabolites of cilostazol were increased by 29 and 69%, respectively. Phenytoin. During the first 2 weeks after starting treatment with omeprazole, it is recommended to monitor the concentration of phenytoin in the blood plasma and continue this monitoring until the end of treatment if the dose of phenytoin is adjusted. Unknown mechanism of drug interaction with Tacrolimus. Increased plasma concentrations of tacrolimus have been reported with concomitant use of omeprazole. It is necessary to carefully monitor the concentration of tacrolimus in the blood plasma, as well as monitor renal function (Cl creatinine) and, if necessary, adjust the dose of tacrolimus. Methotrexate. An increase in plasma levels of methotrexate has been reported in some patients when administered concomitantly with proton pump inhibitors. When using high doses of methotrexate, it is possible to consider temporary withdrawal of omeprazole. Saquinavir/ritonavir. With simultaneous use of omeprazole and saquinavir/ritonavir, saquinavir plasma concentrations increased by up to 70%. This increase in concentration was well tolerated in HIV-infected patients. Other drugs. The absorption of posaconazole, erlotinib, ketoconazole and itraconazole is significantly reduced when co-administered with omeprazole and therefore their clinical effectiveness may be reduced. It is not recommended to use omeprazole in combination with posaconazole, erlotinib, ketoconazole and itraconazole. The influence of other drugs on the pharmacokinetics of omeprazole Inducers of CYP2C19 and/or CYP3A4 isoenzymes Drugs that induce CYP2C19 and CYP3A4 isoenzymes, such as rifampicin and drugs containing St. John's wort, when used together with omeprazole, can lead to a decrease in its concentration in the blood plasma due to accelerated metabolism. Inhibitors of CYP2C19 and/or CYP3A4 isoenzymes The isoenzymes CYP2C19 and CYP3A4 are involved in the metabolism of omeprazole. Concomitant use of drugs that inhibit the CYP2C19 and CYP3A4 isoenzymes, such as clarithromycin and voriconazole, may cause an increase in the concentration of omeprazole in the blood plasma as a result of a decrease in the metabolic rate. Concomitant treatment with voriconazole leads to an increase in the exposure of omeprazole by more than 2 times. Since high doses of omeprazole are well tolerated, dosage adjustment is usually not required. Dose adjustment may be required in patients with severe liver dysfunction and with long-term use. Omeprazole does not affect the metabolism of drugs in which it is carried out using the CYP3A4 isoenzyme, such as cyclosporine, lidocaine, quinidine, estradiol, erythromycin and budesonide. The effect of omeprazole on the following drugs was not revealed: caffeine, theophylline, quinidine, piroxicam, diclofenac, naproxen, metoprolol, propranolol and ethanol. Overdose Single doses of omeprazole 560 mg when taken orally by adults caused symptoms of moderate intoxication. A case is described of taking a single dose of 2400 mg of omeprazole, which did not cause any severe toxic symptoms. With increasing dose, the rate of elimination of omeprazole did not change (1st order kinetics), and no specific treatment was required. Cases of intravenous use of omeprazole in doses of up to 270 mg once a day and up to 650 mg for 3 days have been described during clinical studies without the development of any dose-dependent adverse reactions. Symptoms: dizziness, confusion, apathy, depression, headache, fog; tachycardia; nausea, vomiting, flatulence, diarrhea, abdominal pain. Treatment: symptomatic treatment, if necessary, gastric lavage after oral administration, administration of activated charcoal. There is no specific antidote. Hemodialysis is not effective enough. Routes of administration: Inside, intravenously. Precautions for the substance Omeprazole Before starting therapy, it is necessary to exclude the presence of a malignant process (especially with a stomach ulcer), because Treatment, masking symptoms, can delay the correct diagnosis. If after starting the use of omeprazole there is no improvement in the condition or the heartburn becomes even worse, it is necessary to interrupt treatment and consult a doctor. Patients over the age of 45 with symptoms of heartburn, suffering from heartburn for the first time, can use omeprazole only after consulting a doctor. Omeprazole should be used under the supervision of a physician if one of the following symptoms or conditions is present: decreased body weight without an obvious reason and/or lack of appetite, fatigue; prolonged abdominal pain; history of gastric and/or duodenal ulcer; frequent vomiting; swallowing disorder/pain when swallowing; hematemesis/melena/rectal bleeding; persistent heartburn (more than 3 months); chronic cough, difficulty breathing; jaundice; chest pain (especially chest tightness or pain radiating to the neck or upper limbs) if associated with sweating, difficulty breathing, or dizziness; history of stomach or esophageal cancer in close relatives; liver failure. If any of these symptoms/conditions occur, consult your doctor immediately. The risk of thigh fractures, bones of the wrist and vertebrae. The proton pump inhibitors, especially when they are used in high doses and prolonged use (> 1 year), can moderately increase the risk of thigh fractures, wrist and vertebrae, especially in elderly patients or in the presence of other risk factors. The results of observatory studies suggest that the proton pump inhibitors can increase the total risk of fractures by 10–40%. Patients with the risk of osteoporosis should receive treatment in accordance with the latest clinical recommendations. Hypomagnesemia. In patients taking omeprazole for at least 3 months, severe hypomagnesia was recorded. Clinical manifestations, such as increased fatigue, tanks, nonsense, cramps, dizziness and ventricular arrhythmia, can develop in the form of greased symptoms, which can lead to a late diagnosis of this dangerous state. In most patients, it is possible to achieve an improvement after the use of magnesium -containing drugs and the abolition of the proton pump inhibitors. In patients who are planned for prolonged therapy or an omeprazole with digoxin or other drugs are prescribed, capable of causing hypomagnesia (for example diuretics), the content of magnesium in the blood plasma should be evaluated before the start of therapy and regularly during treatment. Influence on the absorption of vitamin B12. Omeprazole, like all drugs that reduce acidity, can lead to a decrease in the absorption of vitamin B12 (cyancobalamin), because It causes hypo- or ahlorhydria. This must be remembered in relation to patients with a reduced margin of vitamin B12 in the body or with risk factors for violation of vitamin B12 absorption with prolonged therapy. Other effects associated with inhibiting the secretion of hydrochloric acid. In patients taking drugs, reducing the secretion of the glands of the stomach over a long period of time, the formation of glandular cysts in the stomach is more often observed, which pass independently against the background of continuing therapy. These phenomena are due to physiological changes as a result of inhibiting the secretion of hydrochloric acid. A decrease in the secretion of hydrochloric acid in the stomach under the influence of the proton pump inhibitors leads to an increase in the growth of the anorumal intestinal microflora, which in turn can lead to a slight increase in the risk of intestinal infections caused by bacteria of the Salmonella spp genus. and Campylobacter spp., As well as probably the Clostridium Difficile bacteria in hospitalized patients. The skin form of the red lupus of the subacute current. The use of the proton pump inhibitors was associated with very rare cases of the development of the skin shape of the red lupus of the subacute current. In the case of the development of skin lesions, especially in areas open to sunlight, accompanied by joint pain, the patient should immediately seek a doctor’s consultation to resolve the issue of possible termination of the use of omeprazole. The presence of a skin form of the red lupus of the subcutaneous course after the use of inhibitors of the proton pump can increase the risk of developing this disease when using omeprazole. Influence on the results of laboratory tests. Due to a decrease in the secretion of hydrochloric acid, the concentration of chromborn A (CGA) increases. An increase in CGA concentration can affect the results of examinations to detect neuroendocrine tumors. To prevent this influence, it is necessary to temporarily stop using omeprazole 5 days before determining the CGA concentration. Impact on the ability to drive vehicles and machinery. There is no data on the influence of omeprazole on the ability to drive a car or other mechanisms. However, due to the fact that during therapy, dizziness, fuzziness of vision and drowsiness can be observed, caution should be observed when driving vehicles and mechanisms.

Contraindications / Precautions / Effect on reproduction

Omeprazole is contraindicated in cats that are hypersensitive to it.

In animals with liver disease or a history of liver damage, the administration of omeprazole should be carefully considered as the half-life of the drug may be prolonged, requiring dosage adjustments.

The safety of omeprazole during pregnancy in cats has not been established, but studies conducted in rats receiving 345 times the recommended dose did not reveal any teratogenic effects. In laboratory animals receiving very high doses of the drug, an increase in the percentage of embryonic lethality was observed. It is unknown whether omeprazole passes into milk.

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Pharmacokinetics

Omeprazole is rapidly absorbed from the intestine in cats.

The commercially produced drug has enteric-coated granules because the drug is quickly destroyed by stomach acid. The maximum concentration in the blood serum is observed after 0.5-3.5 hours, the onset of action within 1 hour. Omeprazole is distributed throughout the cat's body, but mainly penetrates the parietal cells of the stomach. In humans, approximately 95% of the drug is bound to albumin and acid glycoproteins. It is not known whether omeprazole passes into breast milk.

Omeprazole in cats is metabolized in the liver to at least six different metabolites, which are excreted mainly in the urine, but also enter the bile and are further excreted in the feces. Severe liver dysfunction in cats reduces the first-pass effect of the drug. In a person with normal liver function, the serum half-life is approximately 1 hour, but the therapeutic effect may last up to 72 hours or more.

Cat with chronic renal failure. Help with a treatment plan!

Hello! I really need qualified help! Our cat, a handsome 12-year-old, is seriously ill. The story is like this. Last November, my appetite began to suddenly disappear. First I chose my favorite, then I ate a little of it. At the end of November we took him to the veterinary clinic. They made a diagnosis of constipation, they advised against doing tests - they say, everything is clear here... They treated this same constipation for two weeks. After stopping the treatment (we were injected with hormones there), four days later we refused to eat again. They took me to another clinic, where they already did the tests. Results 12/25/13: blood biochemistry creatinine - 832.5 (normal 60-110) urea - 52.4 (normal 4.8 - total bilirubin - 3.3 (normal 0-4) general blood test hemoglobin 83.5 ( normal 130-180) leukocytes 8.6 (normal 5.5-12) ESR 10 (normal 0-5) leukocyte formula (normal in parentheses) w 0 (0-1), n ​​0 (0-3), s 63 (40-45), l 31 (15-46), m 2 (0-5), e 4 (0-5), b 0 (0-1) Ultrasound: chronic hepatitis, chronic glomerulonephritis Treatment: daily saline 100 ml, piracetam - 2 ml, riboxin - 2 ml, B12-2 ml, glucose 5% - 1 ml, gordox - 1 ml. All this for 4 days intravenously and 4 days subcutaneously (the cat had a hard time after intravenous injections). 5 times from Epoxyl 0.5 ml was added to them. Additional furasemide 0.3 ml was given several times (sometimes he peed 2-3 times a day). The cat felt better. Little by little he began to eat on his own. Like many, I have a problem with Renal Royal Canin food. But and they managed to feed him up to 100 grams of wet food per day (we had to add his favorite meat, cucumber, bell pepper.) After eight days, test results on 01/02/14: blood biochemistry creatinine - 754 (normal 60-110) urea - 36.5 (normal 4.8- bilirubin total. - 4.6 (normal 0-4) amylase - 1228 (normal 400-850) general blood count hemoglobin 123.4 (normal 130-180) leukocytes 6.5 (normal 5.5-12) ESR 59 (normal 0- 5) leukocyte formula (normal in brackets) c 56 (40-45), l 39 (15-46), e 5 (0-5) After the tests, the regimen was slightly changed - saline 100 ml, piracetam - 2 ml, riboxin - 2 ml, B12-2 ml, the rest was canceled (they said they already received a lot of antibiotics?!). Canephron was added, 3 drops 2 times a day. In agreement with the doctor, I added herbs - an infusion of bearberry and orthosiphon stamen. They infused it intravenously, the cat tolerated it well. We were also advised to drip subcutaneously a second time a day - up to 100 ml. His condition is unchanged, his activity is below average, but he still shows interest in his surroundings and eats the same way. Analysis 01/10/14: blood biochemistry creatinine - 873 (normal 60-110) urea - 30.9 (normal 4.8 - total bilirubin - 2.1 (normal 0-4) amylase - 2012.6 (normal 400-850 ) general blood test hemoglobin 81.7 (normal 130-180) leukocytes 6.3 (normal 5.5-12) ESR 30 (normal 0-5) leukocyte formula (normal in parentheses) p 1 (0-3), s 68 (40-45), l 30 (15-46), m 1 (0-5).And then they told us - that’s it, now how long will the body’s reserves last... We continue to drip (saline solution + riboxin + piracetam + B12) , only I’m at a loss - in our condition, how to drip? I tried to switch completely to subcutaneous - I lost my appetite, occasionally selects pieces. We bought dry renal, we haven’t fed dry before, it seems to be gnawing a little at a time. I found your site, I already added: in for a week we give enterosgel (1 tsp 2 times a day), for three days I give kvamatel (1 mg/kg body weight per day) and almagel (1-1.5 ml 2-3 times a day). For ten days we’ve been giving folic acid , we continue canephron. I don’t give the herbal infusion yet (after 15 days I decided to take a break). I don’t take furasemide, he pees 5-6 times a day, the stool has improved for a week now (he poops daily). The pressure is normal (they didn’t measure it, they just listened with a fanendoscope). It seems that nausea has appeared - I vomited three times in the morning (not every day). Please tell me - do I need to change/add any other medications? And how to still drip. Our doctors say - if he pees, then up to 1 liter per day! Will I drown the cat's lungs? How many ml intravenously? and should I drip subcutaneously a second time? I’m confused... There are cats with much better tests in the topics, it’s difficult to transfer their treatment to us. Please adjust our treatment! By the way, our doctors don’t want to hear about Enterosgel and Kvamatel. It’s impossible to connect Ketosteril and Renalcin (I’m afraid they won’t have time to arrive by mail, but we haven’t heard of them).

( 1 rating, average 4 out of 5 )

Application of quamatel

The dosage for each patient is selected individually by the veterinarian, depending on the effects that the drug should have on the body, weight, age, gender, general condition and many other indicators. Self-medication and incorrect “amateur” diagnosis can cause harm.

If you confuse a dog’s symptoms, make a mistake and make an incorrect diagnosis (for example, if you confuse a hyperacid type of gastritis with a hypoacid or, even more so, anacid), then nothing good will end. As mentioned earlier, violation of the dosage and abuse of quamatel can lead to negative, in some cases tragic, consequences. Therefore, it is highly not recommended to give it to an animal yourself.

The effect of quamatel can be extremely negative when interacting with other drugs and medications, the absorption of which is directly affected by the amount and acidity of gastric juice. In addition, the simultaneous use of other drugs that directly act on reducing the level of gastric acidity can lead to the quality of absorption of quamatel. But still, if you strictly follow the course prescribed by a specialist, the animal will tolerate the use of the drug quite well, and there is no doubt that competent treatment will only be beneficial.

>Storage conditions

Kvamatel must be stored in a place protected from direct sunlight, away from animals and children, at a temperature of +10°C to + 25°C.

What to replace it with?

If a cat for some reason cannot use Omez, she is prescribed a medicine that has a similar effect on the pet’s body. And most often Omez is replaced with “Kvamatel”, which also reduces the secretion of gastric juice and helps heal ulcerative lesions of the stomach and duodenum. In addition, the medicine helps with bleeding from the gastrointestinal tract and prevents the release of gastric contents into the respiratory tract, which is especially important before surgery. There are other analogues of Omez, including Ortanol, Omealox, Zerotsid, Omeprazole, Omep, Onex, Helitsid. How to properly use analogues for cats should be checked with a veterinarian and do not self-medicate.

Causes of diarrhea in cats

Diarrhea is considered the main sign of a disorder in the digestive system. This means that the stomach and intestines, for some reason, cannot cope with their functions. But in any case, this is a pathological condition that requires timely treatment.

So why did my cat have diarrhea? What reasons can provoke it? They can be very different:

• incorrect diet or its sudden change.
  If you want to change the animal’s diet, then introduce new foods gradually so that this does not provoke serious disturbances in the functioning of the digestive system. Loose stools can occur in cases where pets are overfed with fatty foods, meat, raw fish, as well as dry food;
• change of water
  . A cat usually gets used to one composition of water. But a sudden change in it, for example, when moving to a country house or while traveling, can lead to the appearance of diarrhea. In these cases, it is recommended to carry the necessary supply of water with you;
• food poisoning .
  This often happens when the cat is allowed to go outside. In the wild, an animal can easily become poisoned as a result of eating game or debris from garbage;
• Diarrhea can occur if your pet has a food allergy
  . Usually during it there is a reduced ability to digest food from the owner’s table;
• Diarrhea is often provoked by various stressful situations.
  Anxiety in a pet can occur when a new animal appears in the house, when staying in special hotels for animals, when visiting a veterinarian, and diarrhea can also be caused by a long absence of the owner;
• ingestion of hair clumps into the stomach
  . But they are even useful, they cause complete cleansing of the stomach;
• diarrhea may be a reaction to medications
  . Each cat has individual characteristics that may manifest themselves when using different medications.

Diarrhea is common in a pregnant cat. If it occurs 1-2 times and then stops, then there is no reason to worry. But if diarrhea bothers the animal for a long time, then you should pay attention to this factor. In the last stages of pregnancy in a cat, diarrhea can be the cause of a pathological process.

It is worth noting! Diarrhea in a cat after childbirth is considered common. It is a consequence of the severe stress that the animal experiences during childbirth. After some time, diarrhea completely stops, the activity of the digestive system is restored.

The causes of diarrhea in cats can be various diseases:

• Quite often, diarrhea is observed in a cat after deworming. Diarrhea is often caused by various parasites - worms, roundworms, worms, Giardia and others. During the presence of helminths, the cat may experience diarrhea with blood and mucus;
• if the animal has diabetes mellitus, which is accompanied by metabolic disorders;
• manifestations of pancreatitis;
• may occur with cancer;
• diarrhea can occur with obstruction and other intestinal pathologies;
• may be a consequence of liver disease;
• may occur in renal failure;
• diarrhea may occur during infectious diseases;
• nausea and diarrhea, which may include bloody discharge, can occur with bacterial infections, for example, with salmonella, clostridium and others;
• Diarrhea in a cat may be a consequence of poisoning of the body.

General characteristics of omez for cats

The search for cures for nausea and stomach disorders continues in both human and veterinary medicine. In the past, antacids started out as simple alkaline products that, when swallowed, acted to neutralize stomach acid. As acid production in the stomach became better understood, antacids were developed that interfered with acid production. Drugs that block H2 receptors were further developed. H2 blockers get their name because they block H2 receptors, which are histamine receptors in the stomach that, when stimulated, cause the production of stomach acid. Blocking the receptor meant blocking acid production. Cimetidine (Tagamet®) was the first H2 blocker released, followed by ranitidine (Zantac®) and famotidine (Pepcid AC®). There are other receptors involved in stimulating acid secretion in the stomach besides the H2 receptors, so even if the H2 receptors are blocked, acid can still be released.

Omez presents a different approach:

proton pump inhibition. The amount of acid ultimately equals the number of protons. The proton pump plays a central role in releasing acid into the stomach and with the help of this pump the stomach acid stops working. Proton pump inhibitors such as omez are the strongest antacids of all. They work not only when the stomach is full/digesting food, but all the time.

Diagnosis of stool

Be sure to pay attention to the type of diarrhea and its color. The fact is that this will help determine what factor caused the appearance of this unpleasant symptom; perhaps it is a serious disease that requires prompt treatment.

So what can the color and consistency of stool tell you:

• Green diarrhea
  . This may indicate the presence of bad processes in the intestines. The main reason may be the use of a low-quality product;
• Black
  . This manifestation occurs in cases when a high level of iron enters the animal’s body, for example, it takes iron-containing drugs, eats raw meat, food containing a large amount of meat additives;
• Yellow diarrhea
  . This indicates insufficient digestion of food;
• Orange or bloody diarrhea in a cat.
  In this case, there is an increased level of bilirubin, which may indicate liver problems;
• White color
  . This symptom may be a consequence of blocking the channels of bile entering the intestinal cavity. In these cases, it is imperative to contact a veterinarian;
• In a cat, diarrhea with mucus
  indicates the presence of an inflammatory process in the cavity of the large intestine;
• Diarrhea with water
  . Increased level of fluid in the intestinal cavity;
• Vomiting and diarrhea of ​​blood in cats
  occurs in the presence of serious illnesses. You should immediately contact a veterinarian for assistance;
• If a cat vomits foam and additional diarrhea occurs
  , then this is a sign of food poisoning.

Note! Quite often, a cat develops diarrhea after drinking milk, but this is not considered a dangerous symptom. The fact is that over time, the production of enzymes in these animals decreases, which leads to poor digestion of dairy products.

Symptoms

Many owners often do not pay attention to their pet’s stool, but this is in vain, because sometimes serious disorders can occur, which as a result can lead to serious problems with the animal’s health.

The most important and obvious symptom of diarrhea is frequent loose stools. But besides this, other signs may also be observed:

• frequent attempts to defecate;
• manifestations of flatulence;
• the presence of mucus and blood in the stool.

Secondary symptoms can also often be observed:

Important! If a cat has diarrhea with an uncharacteristic color, for example, black or green with impurities of blood and mucus, then in these situations you need to immediately visit a veterinarian. These signs may indicate the presence of a serious illness, and the slightest delay can lead to unpleasant consequences.

Drug treatment

How can you quickly stop diarrhea in your pet? In these cases, you can use special medications to treat diarrhea in cats, but you should not use them yourself. You should definitely consult your veterinarian first.

So how to treat your pet, what anti-diarrhea tablets can you use? Let's look at the most effective and popular medications that help quickly cure symptoms of diarrhea.

Metronidazole

Many veterinarians recommend using this drug as little as possible to stop diarrhea at home. Metronidazole puts increased stress on your pet's kidneys and liver. But in some cases the medicine shows increased effectiveness.

It is recommended to use tablets when diarrhea is caused by helminth infection. The drug is also highly effective against bacterial infections.

Affects various simple organisms, among which are:

• Giardia;
• Trichomonas;
• parasitic ciliates (from the genus Balantidium).

But before using it for diarrhea in a cat, you should carefully study the possible side effects:

Activated carbon

If you are thinking about what to give your cat for diarrhea, you can use activated charcoal. People also take this remedy to treat diarrhea. The principle of action of the medicine is based on adsorption, namely, the active elements absorb toxins and harmful components.

This is a harmless medicine that can even be used to treat diarrhea in a pregnant cat. The dosage is usually calculated according to the weight of the pet. But if you give more than the prescribed dose, then nothing bad will happen.

Features of application:

• usually for an animal weighing 2.5 kilograms you can use 3-4 tablets;
• The tablets need to be ground to a powder;
• the powder can be added to cat food or diluted in water;
• then you need to draw the liquid into a syringe and pour it into the pet’s mouth;
• pouring should be done every 5-6 hours until the symptoms of diarrhea disappear.

Smecta

For diarrhea and symptoms of indigestion, you can give your cat Smecta. This medicine is often used for people with diarrhea and dehydration. It has a neutral taste, so there are usually no problems with its use.

In order to cure diarrhea and your pet, you should follow important recommendations when using Smecta:

• For a cat or cat weighing 2.5 kilograms, 1 sachet of the drug should be used;
• the powder must be diluted in a small amount of warm boiled water;
• after the medicine has dissolved, it should be drawn up with a syringe;
• a small amount of liquid is poured directly into the animal's throat.

The drug has no contraindications. For this reason, Smecta can be given to a kitten, and it can also be used to treat diarrhea in a nursing cat.

Enterosgel

Enterosgel appeared in pharmacies quite a long time ago and is extremely popular. The thing is that the medicine has an adsorbent effect, namely, it absorbs harmful components from the walls of the stomach and intestines.

With its help, you can treat not only diarrhea, but also use it as a prophylactic for allergies and diseases associated with disruption of the digestive system.

The drug is safe for cats and cats, it does not cause side symptoms and has no contraindications. An adult cat needs to be given 1 teaspoon of medicine per day, but kittens need ½ teaspoon once a day.

Loperamide

Loperamide is considered a popular antidiarrheal drug used by many travelers. It can also be used to treat diarrhea in animals.

When using Loperamide for cats, you should follow important recommendations:

• for animals weighing 2.5 kilograms, you need to use ½ part of the tablet;
• before giving, the tablet must be broken and ground to a powder;
• The tablet can be given with food or diluted in water and poured into the mouth;
• It is recommended to give kittens in small doses - ¼ or 1/8 of a pill.

Furazolidone

Furazolidone has been used in the treatment of diarrhea for quite some time. The medicine belongs to the group of nitrofurans and has an effective effect on gram-positive and gram-negative bacteria.

Note! The medicine is highly effective against diarrhea pathogens in cats. However, you should be careful when using it, the fact is that the active components place a strong load on the animal’s liver. For this reason, the dose of Furazolidone should be minimal.

The daily dose of the drug should be no more than ¼ tablet, and it must be divided into three doses. The tablet is ground to a powder, diluted in water and poured down the cat’s throat.

Treatment recommendations

Methods for treating diarrhea in cats depend on the cause that provoked these unpleasant symptoms. If this happened due to a change in diet, then over time the digestion will normalize and the stool will be restored. But sometimes stool disorders cause serious illnesses; in these cases, it is worth considering important features of therapeutic therapy:

• It is not recommended to feed the animal on the first day. But at the same time, it must drink a lot of water so that all harmful substances leave the body;
• throughout the course of treatment, the pet should be given boiled food;
• It is worth excluding dairy products, which can cause frequent urge to defecate;
• It is worth additionally including probiotics for cats in treatment therapy, for example, bifidumbacterin. These products can restore the pet’s intestinal microflora;
• You can stop your cat’s diarrhea on your own only in cases where he goes to the toilet no more than 4 times a day. But at the same time he should not have fever, vomiting, nausea;
• You can give a chamomile-based decoction at home. This can speed up the healing process;
• do not feed your pet; all food portions should not be large.

If you follow all of the above recommendations, you can quickly cure your cat’s diarrhea. The main thing is to pay attention to the animal’s condition in time and provide first aid. It is not advisable to self-medicate, because this can cause serious harm to the health of the animal. It is better to immediately take your pet to the veterinarian; a specialist will be able to quickly determine the cause of diarrhea and prescribe effective treatment.

How to use for a pet?

Omeprazole for cats should be used exclusively as prescribed by a veterinarian, who will assess the condition of the animal and prescribe dosages based on its weight. Usually the medicine is prescribed at 0.5-1 mg per kilogram of purring weight. It is recommended to give Omez in the morning and evening. The duration of the treatment course is discussed with the veterinarian and depends on the reaction of the cat’s body to the therapy. Treatment often lasts about 2 weeks and no more. To make it easier to take the tablets, they are first crushed to a powdery consistency and mixed with food. The powder is diluted with water and forcefully poured into the cat’s mouth.

Stomach diseases in cats

The most common disease in cats is inflammation of the gastric mucosa, also called gastritis. It mainly affects adults, but kittens can also get it.

To protect your pets from this terrible disease, you need to know the causes of its occurrence.

The following factors are considered:

• Food too hot or too cold. Cats have a very weak mucous membrane in the stomach, so food for cats should be moderately cooled.
• Long-term stress also negatively affects the health of the animal.
• Poor quality food.
• Too much food has a negative effect on both humans and cats.
• Worms and bacteria.
• A large presence of hairballs in the cat's stomach.
• Some medications have side effects that lead to inflammation. If gastritis may develop due to the medications given to your cat, it is necessary to consult a doctor after the course of treatment.

Composition and properties

The drug Omez is sold in the form of tablets for oral administration and powder intended for the preparation of a suspension.
The active component is omeprazole, the action of which is aimed at suppressing the secretion of hydrochloric acid and having a positive effect on stomach cells. The therapeutic effect in the cat’s body develops within an hour and lasts throughout the whole day. The active ingredient has a bactericidal effect on Helicobacter pylori and under its influence the symptoms are quickly relieved, the healing of defects in the gastrointestinal mucosa is accelerated and the remission of peptic ulcer disease is prolonged. "Omez" has good absorption, and food intake does not affect the bioavailability of omeprazole.