Contraindications and side effects
Taking ketosteril can lead not only to positive results, but also have a negative impact on the dynamics of the disease.
In some cases, if the rules for using the drug are violated, a deterioration in the general well-being of the animal may be observed. The following key points should be considered before taking the medicine:
- An overdose of ketosteril can lead to hypercalcemia - an excess of calcium in the body. This is especially dangerous for small kittens whose skeletons are still poorly developed.
- Some cats (most often purebred cats) may experience increased sensitivity to certain components that make up ketosteril.
- Allergic reactions may occur, for example, an increase in the animal’s body temperature or a more pronounced expression of the general symptoms of the disease.
- Under no circumstances should you start taking the drug in the following cases:
- with an initial excess of calcium in the animal’s body;
- if there is a violation of amino acid metabolism in the body;
- during the animal’s pregnancy or after childbirth, if the cat is feeding kittens;
- It is prohibited to take ketorol simultaneously with tetracycline drugs, as well as drugs containing large amounts of vitamin D.
Side effects and contraindications
Side effects most often occur in cats during an overdose or allergy to the drug. They are accompanied by symptoms such as unsteady gait, frequent and difficult breathing, loss of appetite, cramps, itching, tearing, fever.
This medicine is contraindicated to give to pets in the following cases:
- during pregnancy;
- cats feeding their offspring;
- if you are allergic to one of the components;
- if there is a violation of amino acid metabolism;
- with elevated levels of calcium in the blood;
- simultaneously with tetracycline antibiotics and vitamin D;
- animals under 1 year of age.
Luvitan Long Action
This is another analogue of the drug “Ketosteril”.
"Luvitan Long Action" is recommended for use to prevent deficiency of minerals, amino acids and hypovitaminosis: after long-term illnesses, including seasonal ones, during the recovery period and after operations; for various types of asthenic conditions, fatigue and general weakness, chronic fatigue, reduced immunity; after antibiotic therapy and specific treatment during periods of intense physical and mental stress; with unbalanced or insufficient nutrition; in people living in areas with unfavorable environmental conditions.
Dosage of Ketosteril for cats
Before purchasing Ketosteril, you should consult with a veterinarian who is familiar with your pet's health condition. In most cases, the dosage for animals is the same as the dosage for children. The recommended amount of the drug can be prescribed at the rate of 1 tablet per 5 kg of weight 1 time per day. At the same time, the duration of the course depends on the complexity of the disease and the health characteristics of your cat.
Some owners are mistaken in believing that dividing the tablet into several parts makes the animal feel better. In fact, when the tablet is divided, its protective shell is broken and the properties of the drug are lost. The tablet can only be mixed with water. Due to a possible chemical reaction of the components, adding the medicine to feed, milk and other products is not recommended.
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In order to prevent kidney failure, the dose of Ketosteril for the cat will be prescribed much less. For an adult animal, only 3-4 tablets will be enough for a course of treatment, but the exact prescription should still be made only by a veterinarian. Despite the fact that the tablets do not have a distinct taste, you must be prepared for the fact that your pet will try to spit it out.
During treatment with Ketosteril, experts recommend monitoring the level of calcium and phosphorus compounds in the body. To do this, it is necessary to periodically take appropriate tests and if the permissible values begin to increase, it is necessary to change the dosage of the drug as soon as possible.
You should not neglect proper nutrition, since only an integrated approach will help get rid of the disease. Your cat's diet should contain less animal protein. Also, try to give your pet good food for purebred animals more often.
Of course, with the help of properly selected food, it is possible to achieve an improvement in the condition even without the use of Ketosteril, but the source of the disease will still not be eliminated, so doctors still recommend taking a course of treatment with the drug until complete recovery.
Instructions for use of the drug in veterinary medicine
Since this medicine is intended for the treatment of kidney pathology in humans, there are, accordingly, no instructions for use of the drug for cats. The dosage and treatment regimen for the animal must be calculated by the veterinarian individually for the individual. On average, from 1/4 part to 1 tablet of “Ketosteril” is used per 5 kg of pet weight, depending on the severity of the disease.
Important! The drug "Ketosteril" helps treat chronic renal failure at the initial stage. In case of severe form, it will not have the desired result.
To do this, you need to grind the tablet into powder and dilute it in warm water. Then, using a syringe (without a needle), inject the medicine into the cat’s mouth, being careful not to injure it and making sure that the animal swallows the solution completely.
When is Ketosteril prescribed?
Despite the fact that the box contains instructions for using Ketosteril, only a veterinarian should prescribe the exact dosage for cats and dogs. The most common disease for which this medicine is prescribed is chronic renal failure.
This problem is very common in cats, but in the early stages, it is almost impossible to recognize the disease on your own. The animal's behavior and activity remain the same and do not cause suspicion. For this reason, it is worth visiting a veterinary clinic for examination at least once every 6 months.
The first warning sign that alarms owners is the cat’s increased thirst. With rapidly developing renal failure in cats, a process of dehydration occurs. The pet is thirsty in the absence of extreme heat and food that causes natural thirst. At the same time, the urge to urinate is not frequent, and there is much more urine. Against this background, the cat may experience:
- Poor appetite;
- Attacks of vomiting;
- Lethargy and depression.
If your pet has indications for the use of Ketosteril for a cat, but the cost of the drug is not suitable, the veterinarian may suggest that you team up with the owners of an animal with a similar diagnosis when purchasing. It is quite profitable to buy a package of Ketosteril and cure your cat without extra costs.
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Ketosteril is also used for prolonged unpleasant odor from the mouth, deterioration of coat quality, dry skin, and small mouth ulcers in cats. These symptoms can be either signs of kidney failure or signal another disease.
Another disease for which Ketosteril can help is urolithiasis. If an animal has dysfunctions of the genitourinary system, the drug will help improve the general condition of the body, as well as restore it after surgery, if necessary.
Ketosteril for cats: instructions for use, composition, dosage and price
Ketosteril is a medical drug that is used in human and veterinary medicine for renal failure and other chronic kidney diseases. The main cause of such diseases is a lack of amino acids in the animal’s body. That is why ketosteril is an amino acid complex containing the following basic substances:
- lysine acetate;
- nitrogen;
- threonine;
- phenylpropionic acid;
- calcium salt.
The excipients of the drug include components that promote the most rapid absorption of the drug into the blood and tissues.
Chronic renal failure often develops in older cats, less often in young and middle-aged cats. The causes of chronic renal failure are varied, including genetic predisposition, diseases of the urinary system, poor diet, metabolic diseases and other factors.
The German-made drug Ketosteril was created for the treatment of reduced kidney function in humans, but despite this, it is actively used in veterinary practice.
Ketosteril is produced in the form of oblong tablets, which are film-coated. Active components of the drug: amino acids (L-threonine, L-histidine, L-lysine monoacetate, L-tryptophan, L-tyrosine); alpha-keto analogues of amino acids such as leucine, valine, phenylalanine, isoleucine; alpha-hydroxy analogue of methionine.
Additional components are silicon dioxide, polyvinylpyrrolidone, corn starch, magnesium stearate, talc, polyethylene glycol. The shell is painted yellow. The total content of calcium and nitrogen in one tablet is 50 and 36 mg, respectively.
There are no analogues of Ketosteril for cats.
One box of the drug contains 100 tablets - five blisters of 20 pieces.
The main effect of Ketosteril is to replenish the lack of essential amino acids and normalize metabolism disrupted due to kidney failure. The medicine increases the formation of protein in the body. Ketosteril also reduces the toxicity of protein breakdown products - urea, creatinine, uric acid, etc., the level of which in the blood increases with renal dysfunction.
Indications
Ketosteril is prescribed for cats for chronic renal failure. With this disease, the content of urea and creatinine in the blood is increased, and in the urine, on the contrary, it is decreased. Therefore, chronic renal failure is easy to diagnose based on the results of laboratory tests. In renal failure, nephrons, the structural elements of the kidneys, are destroyed.
This results in an increased filtering load on the remaining healthy nephrons. Glomerular pressure increases in them, and sooner or later they also “fail.”
As a result, the kidneys cannot remove the end products of metabolism; the latter accumulate in the blood, leading to intoxication of the animal’s body, and without treatment, to death.
The first signs of chronic renal failure in a cat are most often gastrointestinal disorders (vomiting, constipation or diarrhea, loss of appetite, darkening of stool), exhaustion, increased blood pressure and associated eye damage (retinal detachment, redness of the whites and iris), deterioration of the coat. which becomes brittle and stops shining.
In the future, frequent urination and severe thirst, an unpleasant odor from the pet, lethargy, drowsiness, mouth ulcers, and convulsions may occur - these are symptoms of advanced renal dysfunction.
In addition to chronic renal failure, a veterinarian can prescribe Ketosteril to a weakened cat with problems with the urinary system, after kidney surgery and for urolithiasis.
The drug is intended for the treatment of humans, so in the package you will not find instructions for using Ketosteril for cats. This medicine is prescribed to animals in much smaller quantities than to humans.
The daily dosage of Ketosteril varies from 1/4 to 1 tablet per 5 kg of pet’s body weight, depending on the nature and stage of kidney damage. The exact dosage and duration of use is always determined by the veterinarian.
How to use Ketosteril for cats? The amount of the drug for one dose should be crushed into powder, mixed with water and given to the muzzle using a syringe without a needle or pipette.
It is not recommended to mix Ketosteril with milk, pate, cream or other products.
Ketosteril is not prescribed for: allergies to the components of the product; cat pregnancy and during breastfeeding kittens; phenylketonuria or other disorders of amino acid metabolism; high calcium levels in the blood.
The medicine should not be used together with quinolone and tetracycline antibiotics, products containing fluoride, iron or estramustine, calcium supplements, vitamin D.
Side effects
Side effects when treating a cat with Ketosteril are rare and can be represented by an allergic reaction or an increase in the level of calcium in the blood (hypercalcemia).
Allergies cause itching, tearing, and fever. With hypercalcemia, the cat feels nauseous, vomits, urinates frequently and drinks a lot, eats poorly or refuses to eat at all.
The animal develops weakness and increases blood pressure.
If the course of taking Ketosteril is long, then it is important to check the level of calcium in the blood every 7-14 days.
Price and reviews
The estimated cost of one box of Ketosteril (100 tablets) is 3,000 rubles. Since much less of the drug is required to treat a cat, it is somewhat expensive to buy a whole package. To save money, many cat owners unite by purchasing Ketosteril by sharing.
Reviews about Ketosteril for cats from veterinarians and pet owners are positive. If you follow all the doctor's recommendations, the use of this drug improves the condition of your pets and helps cope with kidney failure.
In addition, using Ketosteril instead of special expensive feed enriched with amino acids is not only more profitable, but also more effective.
You can buy Ketosteril only with a prescription. Store the drug at an air temperature of no more than 25°C, in a dark and dry place inaccessible to children. Shelf life: 3 years from the date of production.
How to give a pill to a cat
Ketosteril is produced in the form of oblong tablets, which are film-coated. Active components of the drug: amino acids (L-threonine, L-histidine, L-lysine monoacetate, L-tryptophan, L-tyrosine); alpha-keto analogues of amino acids such as leucine, valine, phenylalanine, isoleucine; alpha-hydroxy analogue of methionine.
Additional components are silicon dioxide, polyvinylpyrrolidone, corn starch, magnesium stearate, talc, polyethylene glycol. The shell is painted yellow. The total content of calcium and nitrogen in one tablet is 50 and 36 mg, respectively. There are no analogues of Ketosteril for cats. One box of the drug contains 100 tablets - five blisters of 20 pieces.
general description
Ketosteril is available in the form of yellow oval tablets. A special feature of the tablets is the presence of a food-grade outer shell. It helps preserve the pharmacological properties of the drug components. When it enters the digestive system, it dissolves and promotes the absorption of active substances, thereby accelerating the effect of the drug itself.
Tablets are packaged in blisters of 20 pieces. 5 such blisters are placed in a cardboard box along with instructions for use. Please note that the instructions are written for the use of the medication by humans, so when treating cats, you should mostly follow the recommendations of a veterinarian.
From the date of manufacture, Ketosteril can be stored for 3 years. Any place inaccessible to the sun, children and pets is suitable for storage. There is no need to comply with special conditions; the components of the drug are not susceptible to external factors. You just need to make sure that the air temperature is no more than 25 degrees Celsius.
Ketosteril for cats: indications and instructions for use, reviews, price
Ketosteril is a drug based on essential amino acids that is used to treat chronic renal failure in cats.
The drug was initially developed by the German company Fresenius Kabi for humans, but has also found successful use in veterinary medicine. The medicine is considered unique, as it has no analogues throughout the world.
its peculiarity lies in the amino acids it contains, which have a positive effect on metabolic processes. The drug is a safe drug, but it should not be used without a doctor’s prescription.
general description
Ketosteril is available in the form of yellow oval tablets. A special feature of the tablets is the presence of a food-grade outer shell. It helps preserve the pharmacological properties of the drug components. When it enters the digestive system, it dissolves and promotes the absorption of active substances, thereby accelerating the effect of the drug itself.
Tablets are packaged in blisters of 20 pieces. 5 such blisters are placed in a cardboard box along with instructions for use. Please note that the instructions are written for the use of the medication by humans, so when treating cats, you should mostly follow the recommendations of a veterinarian.
From the date of manufacture, Ketosteril can be stored for 3 years. Any place inaccessible to the sun, children and pets is suitable for storage. There is no need to comply with special conditions; the components of the drug are not susceptible to external factors. You just need to make sure that the air temperature is no more than 25 degrees Celsius.
Composition and action
The basis of the drug is a complex of keto analogues of amino acids, which, when ingested, are converted into essential amino acids necessary for the normal functioning of metabolic and other processes in the animal’s body. The drug contains the following components:
- threonine;
- phenylproionic acid;
- calcium salt;
- lysine acetate, etc.
The composition also includes auxiliary substances:
- talc;
- magnesium stearate;
- corn starch;
- colloidal silicon dioxide, etc.
Kidney failure develops due to a lack of amino acids. When using Ketosteril, a sufficient amount of amino acids enters the body, so the disease stops progressing.
Failures in protein metabolism lead to a serious and deadly disease.
The fact is that in case of violations, the body does not receive the required amount of amino acids, but the drug normalizes the flow of mineral and protein metabolism.
A special pharmacological property of the drug is its ability to remove toxic substances from the body that are formed due to impaired renal function. As a result of using the drug in the body, the level of urea, uric acid, creatinine and creatine decreases. The dynamics of treatment can be easily tracked based on test results.
Note! Ketosteril affects the cause of kidney failure and helps reduce symptoms. But treatment can only be effective with an integrated approach and strict adherence to the diet.
When and how to use
Veterinarians use Ketosteril to treat chronic renal failure. The drug is effective in treating this dangerous disease, especially if used in the early stages.
If the pathology is advanced, the drug will not have the desired result. That is why you need to consult a doctor at the first symptoms of kidney failure.
In addition, it is advisable to undergo examination every six months so as not to miss the onset of the disease.
Ketosteril is also used to treat acidosis (acid-base imbalance) and pathologies associated with metabolic disorders. But you should not use the drug without a doctor’s prescription. It has contraindications and is incompatible with certain types of medications.
Give tablets to pets once a day. The instructions for use describe in what doses Ketosteril should be used for people; for cats, the dose should be calculated by a veterinarian. The average dosage is 1 tablet per 5 kg of weight, but it can be changed by the doctor depending on the condition of the animal, symptoms and stage of the disease, and other factors.
It is recommended to give the tablets whole. Do not crumble or grind them. In this form, the drug is less absorbed by the body and less effective. To give a cat a pill, you need to do the following:
- Wrap your pet in an old towel or blanket so that he does not scratch you during manipulations.
- Lay him on your lap so that his muzzle is on top.
- Open your mouth and place the tablet on the root of your tongue.
- Stroke the animal's neck to trigger the swallowing reflex.
To make the task easier, buy a special device at the pharmacy that is used to give tablets to animals.
Note! Ketosteril is not recommended to be mixed with dry food, canned food and natural products, as the components of the drug may react chemically with them. As a result, they will lose their pharmacological properties, and dangerous compounds may be formed.
Restrictions and contraindications
Ketosteril should not be used for cats in the following cases:
- in case of intolerance to components;
- during pregnancy and lactation;
- with elevated calcium levels.
The medicine affects metabolism and can increase calcium levels in the body. The drug can have a negative effect on the development of offspring, so it is not used for pregnant and lactating cats.
Note! An excess of calcium can interfere with the normal development of the bone skeleton in kittens, so the drug is prohibited for pets under 1 year of age.
If the animal has hypersensitivity, the drug is given in reduced doses. If the body reacts normally and there is no allergy, the dose is gradually increased.
You should not give medication to an animal if there is a violation of amino acid metabolism. In this case, the pet’s condition can only get worse. If the dosage is incorrect, hypercalcemia may occur. The danger of this phenomenon is that the risk of stones in the kidneys and bladder increases. The following symptoms may indicate the development of hypercalcemia:
- rapid breathing;
- convulsions;
- increased nervousness;
- impaired coordination of movements;
- weakness;
- vomiting and nausea;
- lack of appetite.
If you notice such symptoms, stop treatment with Ketosteril and consult your doctor to recalculate the dose. Also, during the period of treatment with the drug, it is necessary to undergo regular tests to monitor the dynamics of the disease, the content of phosphates and other minerals in the blood.
It is strictly forbidden to combine the use of the drug with drugs that contain calcium. You should not combine Ketosteril with certain types of antibiotics (groups of tetracyclines and quinolones).
As a result of their interaction with calcium, compounds are formed that are poorly absorbed by the body. If their use is necessary, then the interval between medications should be at least 2 hours.
How much does it cost and where to buy?
A package of Ketosteril tablets (100 pcs.) will cost 2-3 thousand rubles, depending on the region and pharmacy. The advantage of the drug is that it is sold in regular pharmacies and is available without a prescription.
Since cats usually do not require such a quantity of tablets, owners often sell the leftovers via the Internet, for example, on thematic forums.
This is an opportunity to save money and not pay for medicine that is not useful, but be careful, you may come across scammers.
Owner reviews
Olga, owner of the Scottish Fold cat:
“Kidney failure in our cat was detected at an early stage. Ketosteril was used as the main treatment. After 2 weeks, urea and creatine levels began to improve, and the cat began to recover. The condition has improved noticeably. Now we are seeing a doctor in case the disease returns. Although expensive, it is a very good product.”
Polina, bobtail owner:
“I heard a lot of positive reviews about the medicine, but it was prescribed to us too late. Kidney failure was in progress. We only managed to take 4 tablets, so it’s difficult to judge the effectiveness. Our handsome man went to the Rainbow."
Indications for use
There are not many indications for the use of this drug, namely:
- Protein-energy deficiency. This medical term refers to energy deficiency caused by a lack of macro- and micronutrients. Insufficiency can develop either gradually or abruptly, as a result of starvation. Depending on the degree of the disease, patients may experience swelling, skin atrophy, and hair loss. It is not uncommon for disorders to occur in several systems of internal organs simultaneously.
- Prevention and treatment of disorders caused by changes in protein metabolism due to chronic renal failure, as well as protein deficiency in the diet. As a rule, a similar phenomenon is observed in adults and children over three years of age. Disruption of protein metabolism gradually leads to the accumulation of toxic products (residual nitrogen and its components) in the body and a lack of vital amino acids. Prescribed treatment to relieve the toxic load on the body (diet with limited protein intake) inevitably leads to protein starvation. And, consequently, to the gradually developing protein-energy deficiency described earlier. That is why the drug “Ketosteril”, which replenishes the deficiency of essential amino acids, is indispensable in this case: while simultaneously removing toxic metabolic products, it helps to improve the metabolism of protein and minerals in the body.
It should be noted that the use of the drug is justified when glomerular filtration decreases to a reading of 25 ml/min and below. However, it is also possible to use it in patients in whom this indicator is slightly higher than indicated. Normally, the glomerular filtration rate is in the range of 100-120 ml/min. In order to find out this value, a laboratory test of serum albumin is sufficient.
Price and analogues
The cost of the drug differs slightly depending on the manufacturer:
- tablets Fresenius Kabi Deutschland (Germany) No. 100 – 2525 rubles;
- tablets Beiging Fresenius Kabi Pharmaceutical (China) No. 100 – 2480 rub.
Other products and analogues have similar properties:
- Vita-iodurol;
- Dibikor;
- Histidine hydrochloride;
- Vicein;
- Taufon.
Ketosteril should be used only as prescribed by a veterinarian.
If side effects occur, you should immediately stop taking the medication and inform a specialist to make adjustments to the treatment plan.
special instructions
It is important to regularly monitor calcium levels and monitor the decrease in serum phosphate levels. The drug should be drunk during meals for better absorption and conversion into the corresponding amino acids. It is necessary that the food has enough calories. In patients with hypersensitivity to the components of the drug, allergic reactions were observed in some cases. When co-prescribing drugs that contain calcium, there is a possibility of an increase in this substance in the blood serum. It is necessary to monitor the decrease in serum phosphate levels. In order not to interfere with the absorption of the drug in the intestines, it is not advisable to take it together with drugs that form poorly soluble compounds together with calcium (for example, medications containing estramustine, fluoride, iron, as well as quinolones and tetracyclines)
An interval of at least 2 hours must be maintained between taking drugs and similar medications.
Indications for use and mechanism of action
Ketosteril is recommended by experts for use in the following cases:
- with protein-energy deficiency;
- to eliminate problems associated with metabolic disorders;
- for preventive purposes;
- with urolithiasis;
- for the treatment of renal failure (including the chronic form of the disease).
Only a veterinarian can prescribe the drug to a pet after an examination. Early detection of renal failure is complicated by the lack of obvious signs that breeders can notice.
The specialist has all the necessary tools and equipment, which helps to identify the problem at an early stage of development. Therefore, it is recommended to visit the clinic every six months for a preventive examination.
Cats should be treated with the drug strictly after consultation with a veterinarian.
The principle of operation of the product is based on replenishing the body with essential amino acids, while a minimal amount of nitrogen is used to transport microelements. Active components promote the utilization of nitrogen-containing metabolic products, while simultaneously regulating nitrogen and protein metabolism. Taking the drug leads to a decrease in the content of phosphorus, potassium and magnesium ions in the blood.
Reytoil
"Reytoil" is indicated for use in: hypertriglyceridemia, which is associated with diabetes, excess weight, arteriosclerosis and hypertension; prevention of conditions caused by dyslipidemia; for cardiovascular diseases and their prevention; for arthrosis-arthritis; autoimmune diseases; bone diseases; peptic ulcer of the duodenum and stomach; prevention of malignant diseases; diabetes mellitus and prevention of its complications; diseases of the nervous system; skin diseases; maintaining the health of the fetus and mother (low birth weight, premature birth).
The principle of action of the drug
During the occurrence of kidney pathology, including chronic renal failure, kidney cells (nephrons) are replaced with connective tissue. As a result, the kidneys cease to perform their main function - excretory, which, in turn, leads to a disruption in the water-salt balance of the animal.
He experiences symptoms such as lethargy, thirst, weight loss, nausea, vomiting, etc. That is why the main principle of the drug’s action is the beneficial effect of amino acids on the cat’s body, which consists in inhibiting the process of nephron death, increasing protein formation and restoring metabolism.
Did you know? In medicine, there is officially such a branch as feline therapy or, in other words, treatment with cats. Moreover, different cat breeds have different effects on the human body.
Instructions for use of ketosteril
Ketosteril is produced in the form of tablets coated with a protective coating. After the medicine enters the cat’s body, the protective layer is destroyed and the active components are released.
Veterinarians prescribe ketosteril at the rate of one tablet per 5 kg of animal weight.
Some owners prefer to divide the tablet into several parts and gradually give them to the cat throughout the day. This is not recommended, since if the integrity of the shell is damaged, the beneficial properties of the drug may be lost.
When taking ketosteril, it is also necessary to regularly monitor the level of calcium and phosphorus compounds in the body. Therefore, taking the drug should be under the constant supervision of a veterinarian, who will prescribe all the necessary tests. If the permissible values of these substances increase, the dosage of the drug should be reduced.
In addition, during treatment, the cat must follow a strict diet, in which the amount of animal protein in the food should be reduced as much as possible. In some cases, it is recommended to give the animal special food as often as possible.
Video on how to give a pill to a cat:
Ketosteril instructions for use for cats: dosage and reviews
The reasons why cats develop chronic renal failure are many and varied. Among them are age, genetic predisposition, as well as congenital and acquired diseases of the urinary system.
Ketosteril was not specially developed for cats; the drug was created for the treatment of humans.
But veterinarians clearly recognize it as the best remedy for the treatment of chronic renal failure, a disease that is difficult for animals to tolerate and causes complete disruption of kidney function.
Properties, principle of operation
Ketosteril for cats
The main function of the drug is to supply the body with the necessary amount of amino acids. The active components, participating in the biochemical reaction, make it possible to carry out the process of transferring amino groups without being burdened by the intermediate release of ammonia.
Features of the drug:
- The process involves the breakdown and reduction of lactic acid in the blood.
- Nitrogen-containing products are removed and protein-mineral metabolism is improved.
- Therapy with the drug allows you to reduce the concentration of potassium and magnesium with phosphate.
- Ketosteril removes toxins from the body resulting from kidney failure.
The medicine is produced in the form of coated tablets. Enzymes in the animal's stomach destroy the membrane and release active substances.
Indications for use
The drug is prescribed to cats when there is an increase in urea and creatine in the blood, indicating chronic renal failure.
The drug is prescribed to cats when there is an increase in blood urea and creatine levels.
The disease leads to the death and destruction of nephrons. As a result, the load on healthy structural and functional elements increases, which is why they also stop working.
Metabolic products are no longer excreted from the body.
Intoxication occurs, leading to the death of the cat.
Signs of chronic renal failure | Symptoms |
Primary | Vomiting, diarrhea or constipation, loss of appetite with loss of body weight, darkening of feces |
Redness of the whites of the iris, retinal detachment | |
Increased blood pressure, deterioration of hair condition and hair loss. | |
Secondary | Advanced kidney dysfunction |
Frequent urination, thirst, bad breath, lethargy with drowsiness, ulcers in the mouth, spasms of the limbs |
In addition, Ketosteril is prescribed to animals with acidosis, disruption of the urinary system, and the formation of stones in it.
Directions for use, dosage for cats
Kidney failure is dangerous for felines. An accurate diagnosis can be made after examination.
Important! Animals are often hypersensitive to the composition of the tablets. Therapy is carried out starting with small dosages.
https://www.youtube.com/watch?v=kv967fS6UPQ
Rationing at the rate of 1/2 tablet per 2.5 kg of weight no more than once a day. It is better to crush the drug. It is more convenient to give using a syringe, mixed with water.
For prevention and as a secondary treatment for other diseases, a smaller dose of 1/8 to 1/4 tablet is given once a day. On average, a preventive course requires no more than 4 tablets.
Important! It is necessary to give the product strictly in accordance with the instructions for use.
Contraindications and possible side effects
The product must be given strictly in accordance with the instructions for use.
The use of the drug is not allowed:
- young animals up to one year old;
- pregnant and lactating individuals;
- in case of violation of amino acid metabolism;
- individual intolerance to components.
In case of emergency, it is used for elevated calcium levels.
It is not recommended to mix the medicine with food due to a possible reaction of the compounds.
Do not combine with tetracycline and quinolone antibiotics, fluoro-, iron-, estramustine- or calcium-containing drugs and vitamin D.
During the interaction, compounds are formed that are poorly absorbed by the body, so an interval between doses of medication must be maintained for more than 2 hours.
Overdose is extremely rare, but there are side effects:
View | Hypercalcemia | Allergy |
Symptoms | Shortness of breath, poor coordination when walking, thirst, refusal to eat, muscle spasms, aggressiveness | Itching, hyperthermia, lacrimation |
The occurrence of such symptoms requires contacting a veterinarian.
Composition and release form
Ketosteril is packaged in blisters of 20 pieces, packed in cardboard boxes. The package contains 5 blisters and instructions for use.
Ketosteril is packaged in blisters of 20 pieces
The medicine tablet contains:
It is an oval, double-convex, pale yellow tablet with a protective film coating that protects the gastrointestinal mucosa from irritation.
Cost and analogues of Ketosteril
There is no drug that is completely identical in composition. Pharmaceutical companies produce products with similar effects.
The cost of the medicine depends on the country of manufacture and has a slight difference:
- Fresenius Kabi, Germany – about 2350 rubles;
- Labesfal Laboratorios Almiro SA, Portugal - approximately 2400 rubles.
Properties similar to Ketosteril:
- solutions: Hepasol-Neo, Binocrit, Nephrotect;
- tablets: Furosemide, Ketoaminol.
Storage features and safety measures
The medicinal properties of the drug do not change for 36 months from the date of release, subject to storage conditions:
- It is necessary to completely exclude exposure to sunlight.
- The ambient temperature should be from 0 to +25 degrees.
- Humidity should not exceed 60%.
The storage location must be isolated from children and animals. Do not place the medicine near food.
Reviews from owners and veterinarians about the drug
Feedback from cat owners and breeders about the drug is positive. Its high efficiency is noted in case of timely use.
At the same time, it is indicated that even if treatment is started early, the animal has to take the drug for life.
Veterinarians claim that the original medicine works better than analogues and substitutes. It is recommended to examine pets in a timely manner so as not to miss the opportunity to save them. At the same time, the possibility of side effects is noted, which must also be included in the risk percentage.
Conclusion
Ketosteril contains all the components important for the functioning of the urinary system and can help the animal cope with the disease. Using medication without prescription and supervision by a specialist is dangerous for the cat’s life.
Source: https://KotikDoma.com/bolezni-u-koshek/mochepolovye-bolezni/ketosteril-dla-kosek.html
Analogues and prices
The drug "Ketosteril" is quite expensive. Its cost is 3000 rubles. Since a whole package of medicine is not needed to treat one cat, animal owners are trying to unite and purchase it for several pets. There are no complete analogues of Ketosteril, but there are several medicines whose effects are very similar.
These include:
- "Gepasol-Neo" is a drug in the form of a solution that normalizes metabolism and prevents liver diseases.
- “Ketoaminol” is a tablet product that replenishes amino acid deficiency and restores metabolism.
- "Nephrotect" is a solution that contains essential and essential amino acids and helps produce protein.
"Ketosteril" enjoys a good reputation among cat owners and veterinarians during the treatment of chronic renal failure or other kidney diseases associated with metabolic disorders.
If you follow all the recommendations of your veterinarian, this medicine will help your pet quickly recover and improve its well-being.
Price and reviews
The estimated cost of one box of Ketosteril (100 tablets) is 3,000 rubles. Since much less of the drug is required to treat a cat, it is somewhat expensive to buy a whole package. To save money, many cat owners unite by purchasing Ketosteril by sharing. Reviews about Ketosteril for cats from veterinarians and pet owners are positive. If you follow all the doctor's recommendations, the use of this drug improves the condition of your pets and helps cope with kidney failure. In addition, using Ketosteril instead of special expensive feed enriched with amino acids is not only more profitable, but also more effective.
Method of use and dosage
According to the instructions included with the drug, these pills should be taken exclusively orally and not chewed. It is better to drink this remedy while eating. The dosage is prescribed by the attending physician; it depends on the individual clinical characteristics and the patient’s weight.
The recommended average dose of the medicine for an adult (weighing up to seventy kilograms) and a child over three years old is one tablet per five kilograms of body weight per day. For an adult patient who weighs seventy kilograms, the average dosage is four to eight tablets three times. During therapy, the daily amount of food should contain the following amount of protein: for children from three to ten years old, 0.8 grams per kilogram of weight, and for those over 10 years old, from 1 gram.
Contraindications and precautions
Ketosteril for cats is rightfully called one of the most effective drugs that help in the fight against kidney failure.
It is very difficult to diagnose kidney failure at an early stage, but as the disease progresses, the symptoms become more and more obvious.
Even in the cold season and in the absence of salty food in the animal’s diet, the cat is constantly thirsty. Naturally, this leads to a significant increase in the amount of urine excreted, but the animal does not sit on the tray more often. This is because the kidneys are unable to concentrate the increasing volume of urine. Almost immediately, there is a deterioration in the cat’s general well-being, loss of appetite, a sharp decrease in body weight, and possible nausea and vomiting.
Ketosteril can also be taken if there is an unpleasant odor from the animal’s mouth for a long time, the appearance of ulcers on the mucous membranes, a decrease in the thickness of the fur and dry skin. These symptoms can not only signal a violation of protein metabolism in the body, but also be additional signs of the development of renal failure.
Taking ketosteril can lead not only to positive results, but also have a negative impact on the dynamics of the disease. In some cases, if the rules for using the drug are violated, a deterioration in the general well-being of the animal may be observed.
The following key points should be considered before taking the medicine:
- An overdose of ketosteril can lead to hypercalcemia - an excess of calcium in the body. This is especially dangerous for small kittens whose skeletons are still poorly developed.
- Some cats (most often purebred cats) may experience increased sensitivity to certain components that make up ketosteril.
- Allergic reactions may occur, for example, an increase in the animal’s body temperature or a more pronounced expression of the general symptoms of the disease.
- Under no circumstances should you start taking the drug in the following cases:
- with an initial excess of calcium in the animal’s body;
- if there is a violation of amino acid metabolism in the body;
- during the animal’s pregnancy or after childbirth, if the cat is feeding kittens;
- It is prohibited to take ketorol simultaneously with tetracycline drugs, as well as drugs containing large amounts of vitamin D.
An amino acid combination product that supplies the human body with the necessary amino acids without burdening it with nitrogen is Ketosteril tablets. Often the drug is used to treat pathologies caused by renal failure. The medicine has a certain dosage and a number of features that need to be taken into account in the process of therapeutic measures.
The medication helps restore metabolic processes disrupted by a lack of amino acids due to kidney dysfunction. The tablets help synthesize protein, reduce the toxic effects of by-products of protein metabolism, and alleviate the symptoms of chronic kidney pathologies. To get the results described above, you need to know how to use the drug correctly. This medicine:
- reduces proteinuria;
- relieves symptoms of uremia;
- has a positive effect on phosphorus-calcium metabolism;
- improves glucose metabolism;
- reduces creatinine levels.
Name of component Quantity (mg)
Active elements: leucine alpha-keto analogue isoleucine alpha-keto analogue methionine alpha-hydroxy analogue valine alpha-keto analogue phenylalanine alpha-keto analogue L-threonine L-histidine L-tyrosine L-lysine monoacetate L-tryptophan | 1016759866853383010523 |
Additional substances: magnesium stearate, corn starch, colloidal silicon dioxide, povidone, polyethylene glycol 6000 tal, soluble povidone | 15444,4612,819,5743,2 |
Tablet shell: triacetin talc methyl methacrylate, butyl methacrylate, dimethylaminoethyl methacrylate macrogol 6000 titanium dioxide quinoline yellow | 0,439,15,91,487,40,72 |
nitrogen | 36 |
Amount of calcium | 50 (or 1.25 mmol) |
Ketosteril provides the body with all the necessary amino acids and does not burden the body with residual nitrogen (a set of non-protein nitrogen, which consists of uric acid, urea, amino acid nitrogen, creatinine, creatine).
The tablets contain ketone analogs of amino acids that undergo transamination to L-amino acids naturally. The drug utilizes metabolic products that contain nitrogen, promotes protein anabolism while reducing serum urea concentration.
Improves mineral and protein metabolism in the body.
When treated with Ketosteril, the concentration of magnesium, phosphate and potassium decreases.
When the patient's condition improves, the dosage of aluminum hydroxide, which was prescribed for acidosis (increased acidity), should be gradually reduced. This is necessary so that the acid-base balance is not disturbed.
In most cases, the drug is prescribed to patients with a glomerular filtration rate of less than 25 ml per minute. As a rule, Ketosteril tablets are used in the following situations:
- prevention and treatment of pathologies that are caused by insufficient or altered protein metabolism in chronic renal failure (in adults and children from 3 years of age);
- protein-energy malnutrition;
- protein starvation caused by a special diet to reduce the toxic load in chronic renal failure.
According to the instructions that come with the drug, the tablets should be taken orally and not chewed. It is better to drink the product during meals. The dosage is prescribed by the attending physician; it depends on individual clinical indicators, as well as on the patient’s weight. Recommended average dose of medication:
- adult and child over 3 years of age: 1 tablet per 5 kilograms of body weight (per day) or 100 mg/kg;
- The average dose for an adult patient weighing 70 kg is 4-8 tablets three times a day.
During treatment, the daily amount of food should contain the following amount of protein:
- child from 3 to 10 years: 1.4–0.8 g per kilogram of weight;
- patients over 10 years of age: 1–0.6 g per kilo.
Ketosteril for cats
The amino acid combination product is used not only for humans. Today, Ketosteril is one of the most effective drugs used to treat kidney failure in cats. This disease is very dangerous for the animal, because kidney function can completely stop. The correct diagnosis can only be made by a veterinarian after a detailed examination.
Some cats have hypersensitivity to the components of the tablets, so therapy is carried out carefully, prescribing a small dosage. When an animal has an excess amount of calcium, you should not give it the drug.
The use of a combination medication is prohibited in case of a serious disorder of amino acid metabolism. The dosage for a cat is identical to the amount of the drug for a small child - 1 tablet per 5 kg of body weight once a day.
The duration of therapy is prescribed by the doctor.
Drug Result of interaction with Ketosteril
Preparations containing calcium | The likelihood of hypercalcemia (increased calcium in the blood, during which connective tissue grows in the kidneys and stones form). |
Quinolones | The risk of a negative reaction with calcium, which is in the tablets. |
Tetracyclines | May reduce the absorption of the components of the amino acid preparation. |
Medicines with fluoride, antibiotics | Formation of poorly soluble complexes with calcium. |
Iron products | Impaired absorption of the active elements of the drug. |
The drug Ketosteril in some isolated cases causes a side effect in the form of the development of hypercalcemia - an increase in the concentration of calcium in the blood plasma. To get rid of this problem, it is recommended to reduce the amount of vitamin D used. If this does not give results, then reduce the dosage of amino acid medication and other medications containing calcium.
Contraindications
According to the instructions, there are a number of conditions and diseases for which it is prohibited to take tablets with amino acids. The drug is not prescribed in such cases as:
- patient age under 3 years;
- presence of hypercalcemia;
- violation of amino acid metabolism;
- high sensitivity to the composition of the tablets;
- pregnancy, lactation period;
- in the presence of hereditary phenylketonuria, it is taken into account that the tablets contain phenylalanine.
The amino acid complex product is sold only with a doctor's prescription. The shelf life is 3 years. The drug should be stored in a dry place, well protected from sunlight at a temperature of no more than 25 degrees.
Analogues of Ketosteril
There are a number of effective analogues of Ketosteril. The most popular “understudies” of the medication are:
- Gepasol-Neo solution is a drug with hepatoprotective, metabolic and detoxification effects. It is produced as a solution of amino acids, of which there are more than the “original”.
- Another analogue of Ketosteril is Binocrit. This is a solution with hematopoietic action for subcutaneous or intravenous injection. The main active ingredient is epoetin alfa. Used to treat anemia in children and adults caused by chronic renal failure.
- Furosemide is a strong drug with a diuretic effect. Available in the form of tablets and solution for injection. It is used to eliminate swelling caused by renal or heart failure.
- Nephrotect solution for infusion includes essential and essential amino acids. The drug is prescribed to replenish amino acids and treat kidney failure.
Ketosteril price
You can purchase tablets at any pharmacy kiosk or order from an online pharmacy using a catalog. The cost of the medicine depends on the specific place of sale. Below is a table with approximate prices for Ketosteril No. 100 50 mg in pharmacies in Moscow and the region.
ManufacturerPrice, rubles
Fresenius Kabi, Germany | 2292–2500 |
Portugal, Labesfal Almiro/Binnopharm | 2200–3158 |
Reviews
Composition and action
The basis of the drug is a complex of keto analogues of amino acids, which, when ingested, are converted into essential amino acids necessary for the normal functioning of metabolic and other processes in the animal’s body. The drug contains the following components:
- threonine;
- phenylproionic acid;
- calcium salt;
- lysine acetate, etc.
The composition also includes auxiliary substances:
- talc;
- magnesium stearate;
- corn starch;
- colloidal silicon dioxide, etc.
Kidney failure develops due to a lack of amino acids. When using Ketosteril, a sufficient amount of amino acids enters the body, so the disease stops progressing. Failures in protein metabolism lead to a serious and deadly disease. The fact is that in case of violations, the body does not receive the required amount of amino acids, but the drug normalizes the flow of mineral and protein metabolism.
A special pharmacological property of the drug is its ability to remove toxic substances from the body that are formed due to impaired renal function. As a result of using the drug in the body, the level of urea, uric acid, creatinine and creatine decreases. The dynamics of treatment can be easily tracked based on test results.
Note! Ketosteril affects the cause of kidney failure and helps reduce symptoms. But treatment can only be effective with an integrated approach and strict adherence to diet.
Ketosteril for cats: use and dosage
Ketosteril is a medicinal product containing essential amino acids.
The main purpose is to treat kidney failure diagnosed in pets. The development of the Fresenius Kabi company (Germany) was originally intended for people, but over time it found its home in veterinary medicine.
Instructions for use of Ketosteril for cats indicate its safety, but uncontrolled use is contraindicated.
General information
The drug is presented to the consumer in oval, yellowish tablets, which are placed in a special food coating. The significance of the latter is to preserve the pharmacological properties of the main active ingredients. This coating dissolves only in the digestive system, while the active substances are quickly absorbed, accelerating the therapeutic process.
The manufacturer packs tablets of 20 pieces in blisters. There are 5 of them in a cardboard box, and instructions for the user are always included. The generally established dosage is adjusted by a veterinarian examining the domestic cat, after which the course of treatment is determined.
Ketosteril is suitable for use for 3 years from the date indicated on the packaging. The drug is stored in a dark place where direct sunlight does not reach, children and pets cannot reach it (for their own safety). The optimal temperature for long-term maintenance of the medication is maintained within +25 degrees.
Composition features and action
The development of kidney failure is a consequence of insufficient amino acids. The basis of the drug is represented by substances that, when entering the animal’s body, are converted into essential amino acids, which are responsible for the normal course of important metabolic processes. These components include:
- phenylpropionic acid;
- threonine;
- lysine acetate;
- calcium salt.
The medication also contains additional components in the form of corn starch, talc, colloidal silicon dioxide, and magnesium stearate.
As a result of timely therapy, the disease stops developing, and the general condition of the animal improves. His body receives amino acids in the required quantities, which stabilize important vital processes.
It is worth noting that Ketosteril, in addition to its effective therapeutic effect, neutralizes and removes dangerous toxins in a short time.
They are formed in large quantities against the background of a malfunction of the kidneys. During treatment, the level of substances such as creatine, creatinine, uric acid, and urea is normalized.
Positive dynamics in therapy are easily determined by the results of regularly performed tests.
The drug affects the cause that led to the development of renal failure, eliminating unpleasant symptoms. Effective treatment occurs only as a result of an integrated approach to the problem with adherence to a strict diet.
Rules of application
The main purpose of Ketosteril is to eliminate the pathological process in the kidneys , which often becomes chronic.
A positive result will not be long in coming if therapy is carried out at the very beginning of the disease. In advanced cases, the desired result is achieved much less often.
It is for this reason that veterinarians strongly recommend that your domestic cat be examined at the first symptoms indicating kidney failure.
The medication is often included in the prescription sheet for diagnosed acidosis (failure of acid-base balance) and metabolic disorders. It should be understood that the drug has a number of contraindications; it is prohibited to combine it with certain types of medications. Accordingly, the therapeutic regimen is determined only by a specialist.
The tablets are fed to animals once a day. The average dosage indicated in the instructions for use is one pill per 5 kg of the total weight of the animal. However, this indicator can be changed by a specialist who takes into account the stage of the disease that has developed, the general condition of the cat, and the symptoms that have appeared.
The tablets must be consumed whole. They are not crushed or crumbled, as this leads to insufficient absorption of active substances and minimal effect. There is an algorithm of actions that facilitates the procedure for introducing the drug into the animal’s oral cavity:
- The cat is wrapped in a blanket or towel, this prevents its active movement during the procedure, while the person will remain without scratches.
- The pet is placed on the person’s lap with its muzzle facing up.
- The mouth is carefully opened and a tablet is placed on the root of the tongue.
- Light stroking movements on the neck will provoke a swallowing reflex and the drug will enter the digestive tract.
The task can be simplified if you use a special product designed for feeding medications in dry form.
Ketosteril is not mixed with natural products, canned food or feed due to the high probability of a chemical reaction. This can lead to a decrease in pharmacological properties and the creation of dangerous compounds.
Contraindications and restrictions
There are conditions in four-legged pets when they are not allowed to be given Ketosteril. These include:
- elevated calcium levels;
- pregnancy and lactation period;
- individual intolerance to any of the constituent components, allergic reaction to them.
Therapy can negatively affect the condition of future offspring, lead to termination of pregnancy, and the birth of kittens with physical injuries.
Thus, due to its effect on metabolic processes, the medicine helps to increase the amount of calcium. Hypercalcemia contributes to the formation of bladder and kidney stones.
The following symptoms indicate this condition:
- rapid breathing;
- convulsive syndrome;
- lack of appetite, nausea accompanied by vomiting;
- nervousness uncharacteristic for a pet;
- general weakness with poor coordination of movements.
It is important to remember that an excess of calcium in a kitten’s body disrupts the process of strengthening the bone skeleton. Therefore, the medication is not used on animals under 1 year of age.
In some cases, with increased sensitivity, a reduced dose normalizes the cat’s condition, and treatment does not have to be interrupted. In such a situation, the veterinarian carefully monitors the dynamics of recovery, gradually increasing the dosage to the therapeutic norm.
If the indicated symptoms occur simultaneously with the deterioration of the cat’s condition, you should stop therapy and contact your veterinarian, who will review the prescription and adjust the dose of Ketosteril. Throughout the course of treatment, tests are required to monitor phosphates and other minerals in the blood.
As for compatibility, such a medication is not allowed to be used simultaneously with calcium-containing products.
The parallel use of Ketosteril by a cat with antibiotics (quinolones, tetracyclines) is inappropriate.
If it is necessary to take the indicated drugs simultaneously, to prevent the appearance of dangerous compounds, the interval between their use should be 2 hours or more.
Opinions from cat owners and veterinarians
There are many positive reviews about Ketosteril as a veterinary medicine for home use.
If the specialist’s recommendations are strictly followed, the animals’ condition quickly returns to normal, and the acute symptoms accompanying renal failure are eliminated.
Moreover, the use of such a product as a source of necessary amino acids is more profitable in comparison with special expensive feeds.
https://www.youtube.com/watch?v=1YK8bRFq_pw
Kidney failure is a common problem in domestic cats. Ketosteril does not cure the problem, but it enhances the effect of the therapy. It saturates the pet’s body with the necessary amino acids, improving general condition and strengthening the immune system. There are also side effects, I know this from personal experience. In this case, it is important to follow the dosage and rules of use.
Instructions for use Ketosteril for cats classifies it as a medication with a powerful effect, which is observed in the presence of two conditions. Therapy is carried out in the early stages of the development of pathology, and there is also a risk of lifelong use of such a medicine.
I promptly consulted a specialist and the cat was diagnosed with impaired kidney function, but at an early stage. The basis of therapy was Ketosteril. After just 10 days, tests showed a significant improvement in creatine and urea levels. Yes, the drug is expensive, but its effect is positive.
Source: https://dalmspb.com/zdorove/ketosteril-dlya-koshek-primenenie-i-dozirovka-100960/
Composition and release form
This product is produced in the form of yellow biconvex tablets, characterized by an elongated shape. The pills of this drug are film-coated. One blister contains twenty pieces. Five blisters are placed in a sealed bag, and then the product is packaged in a cardboard box.
The composition of one Ketosteril pill looks like this: an alpha-keto analogue of leucine, isoleucine, methionine and valine along with histidine, tyrosine, lysine and tryptophan. Additional components are magnesium stearate along with corn starch, povidone dioxide and talc.
The composition is described in detail in the instructions for use of Ketosteril. We'll look at reviews about it below.
Directions for use, dosage for cats
Kidney failure is dangerous for felines. An accurate diagnosis can be made after examination.
Important! Animals are often hypersensitive to the composition of the tablets. Therapy is carried out starting with small dosages.
Rationing at the rate of 1/2 tablet per 2.5 kg of weight no more than once a day. It is better to crush the drug. It is more convenient to give using a syringe, mixed with water.
For prevention and as a secondary treatment for other diseases, a smaller dose of 1/8 to 1/4 tablet is given once a day. On average, a preventive course requires no more than 4 tablets.
Important! It is necessary to give the product strictly in accordance with the instructions for use.